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临床试验/NCT04700215
NCT04700215Unknown不适用

Comparison of Effectiveness of Bilevel Positive Airway Pressure and Incentive Spirometry in Reducing Post CABG Surgery Pulmonary Complications

Chaudhry Pervaiz Elahi Institute of Cardiology2 个研究点 分布在 1 个国家目标入组 350 人开始时间: 2021年3月1日最近更新:
适应症

试验速览

阶段
不适用
发起方
入组人数
350
试验地点
2
主要终点
Post CABG pulmonary complications

研究概览

简要总结

To evaluate the effect of Bi-level Positive Airway Pressure (BiPAP) and Incentive Spirometry (IS) in post CABG patients.

详细描述

As postoperative pulmonary complications are major concern in cardiac surgery patients and our local data is deficient for making better management guidelines. My study aims to provide a base for future research on this dimension and to decide better management plan for post cardiac surgical pulmonary complications. The hypothesis is Post extubation BiPAP is more effective than Incentive Spirometry (IS) in reducing postoperative pulmonary complications in cardiac surgical patients and the purpose of the study is to evaluate the effect of Bi-level Positive Airway Pressure (BiPAP) and Incentive Spirometry (IS) in cardiac surgical patients.

This Randomized Controlled Trial (RCT) study will be conducted at Chaudhary pervaiz elahi institute of cardiology ICU multan.

A sample size of 350 patients will be taken and effect of BiPAP and Incentive spirometry will be studied in reducing pulmonary complications post CABG surgery. Data will be analyzed through SPSS. For quantitative variables, mean and standard deviation will be calculated and for qualitative variables, frequency and percentage will be calculated. Chi square test will be used to estimate association between qualitative variables. A p value < 0.05 will be significant.

研究设计

研究类型
Interventional
分配方式
Randomized
干预模型
Parallel
主要目的
Prevention
盲法
Double (Care Provider, Outcomes Assessor)

入排标准

年龄范围
20 Years 至 60 Years(Adult)
性别
All
接受健康志愿者

入选标准

  • CABG patients
  • Patient willing to study
  • Patients planned for on-pump cardiac surgical procedures
  • Both genders (Male & Female)
  • Age 20-60 years
  • Ejection fraction 40-60%

排除标准

  • Patients with valvular lesions
  • Off-pump cardiac surgery
  • Refusal to give consent for BiPAP
  • Emergency surgery
  • Previous cardiac surgery
  • Obesity BMI>30
  • ASA status V

结局指标

主要结局

Post CABG pulmonary complications

时间窗: 06 months

To see the effect of BiPAP and IS in reducing post CABG pulmonary complications

次要结局

未报告次要终点

研究者

发起方
Chaudhry Pervaiz Elahi Institute of Cardiology
申办方类型
Other Gov
责任方
Principal Investigator
主要研究者

Muhammad Imran Khan

Doctor Muhammad Imran Khan

Chaudhry Pervaiz Elahi Institute of Cardiology

研究点 (2)

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