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Clinical Trials/NCT04700215
NCT04700215
Unknown
Not Applicable

Comparison of Effectiveness of Bilevel Positive Airway Pressure and Incentive Spirometry in Reducing Post CABG Surgery Pulmonary Complications

Chaudhry Pervaiz Elahi Institute of Cardiology1 site in 1 country350 target enrollmentMarch 1, 2021

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Pulmonary Complications
Sponsor
Chaudhry Pervaiz Elahi Institute of Cardiology
Enrollment
350
Locations
1
Primary Endpoint
Post CABG pulmonary complications
Last Updated
4 years ago

Overview

Brief Summary

To evaluate the effect of Bi-level Positive Airway Pressure (BiPAP) and Incentive Spirometry (IS) in post CABG patients.

Detailed Description

As postoperative pulmonary complications are major concern in cardiac surgery patients and our local data is deficient for making better management guidelines. My study aims to provide a base for future research on this dimension and to decide better management plan for post cardiac surgical pulmonary complications. The hypothesis is Post extubation BiPAP is more effective than Incentive Spirometry (IS) in reducing postoperative pulmonary complications in cardiac surgical patients and the purpose of the study is to evaluate the effect of Bi-level Positive Airway Pressure (BiPAP) and Incentive Spirometry (IS) in cardiac surgical patients. This Randomized Controlled Trial (RCT) study will be conducted at Chaudhary pervaiz elahi institute of cardiology ICU multan. A sample size of 350 patients will be taken and effect of BiPAP and Incentive spirometry will be studied in reducing pulmonary complications post CABG surgery. Data will be analyzed through SPSS. For quantitative variables, mean and standard deviation will be calculated and for qualitative variables, frequency and percentage will be calculated. Chi square test will be used to estimate association between qualitative variables. A p value \< 0.05 will be significant.

Registry
clinicaltrials.gov
Start Date
March 1, 2021
End Date
August 30, 2022
Last Updated
4 years ago
Study Type
Interventional
Study Design
Parallel
Sex
All

Investigators

Sponsor
Chaudhry Pervaiz Elahi Institute of Cardiology
Responsible Party
Principal Investigator
Principal Investigator

Muhammad Imran Khan

Doctor Muhammad Imran Khan

Chaudhry Pervaiz Elahi Institute of Cardiology

Eligibility Criteria

Inclusion Criteria

  • CABG patients
  • Patient willing to study
  • Patients planned for on-pump cardiac surgical procedures
  • Both genders (Male \& Female)
  • Age 20-60 years
  • Ejection fraction 40-60%

Exclusion Criteria

  • Patients with valvular lesions
  • Off-pump cardiac surgery
  • Refusal to give consent for BiPAP
  • Emergency surgery
  • Previous cardiac surgery
  • Obesity BMI\>30
  • ASA status V

Outcomes

Primary Outcomes

Post CABG pulmonary complications

Time Frame: 06 months

To see the effect of BiPAP and IS in reducing post CABG pulmonary complications

Study Sites (1)

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