Effect of Neurofeedback Training on Fatigue Symptoms in Post-COVID Patients with Post-Exertional Mailaise (PEM)
- Conditions
- U08.9U09.9U10.9Personal history of COVID-19, unspecifiedPost COVID-19 condition, unspecifiedMultisystem inflammatory syndrome associated with COVID-19, unspecified
- Registration Number
- DRKS00032602
- Lead Sponsor
- niversitätsklinikum Heidelberg, Klinik für Allgemeine Innere Medizin und Psychosomatik (Innere II)
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- All
- Target Recruitment
- 45
Patients must have a current post-COVID diagnosis with fatigue and PEM symptoms
Patients who already suffered from previous illnesses that caused fatigue and other ongoing chronic diseases before the COVID infection were excluded from the patient groups. People who suffer from depressive and/or anxious symptoms in addition to fatigue are excluded from the patient groups. This is determined using cut-off scores in the PHQ-9 and GAD-7 (<10 each).
In addition, participants who have already received neurofeedback training must be excluded, since previous experience would influence the result. As a further exclusion criterion, there must be no psychiatric diagnosis (diagnosis groups according to ICD-10: F10-F19 mental and behavioral disorders caused by psychotropic substances; F20-F29 schizophrenia, schizotype and delusional disorders; F30-F39 affective disorders; F40. phobic disorders; F41. Other anxiety disorders; F42.- Obsessive-compulsive disorder). An adjustment disorder (F43) is not an exclusion criterion.
Prior to recruitment, participants will be excluded who are taking the following medications. These are:
• Sympathomimetics (including oral or inhaled beta-2 mimetics)
• Sympatholytics (including beta blockers)
• Parasympathomimetics
• Parasympatholytics
• Sinus node inhibitors (including ivabradine)
• Antiarrhythmics
• Opioids
• Glucocorticoids
• Antidepressants
• Hypnotics/sedatives
• neuroleptics
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method
- Secondary Outcome Measures
Name Time Method