Evaluating the effect of Acetazolamide on the prevention of post-operative Acute Kidney Injury following Coronary Artery Bypass Grafting surgery
Phase 3
Recruiting
- Conditions
- Acute kidney injury.Acute kidney injuryN99.9
- Registration Number
- IRCT20151227025726N21
- Lead Sponsor
- Shahid Beheshti University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- All
- Target Recruitment
- 70
Inclusion Criteria
It will be performed on patients who refer to Masih Daneshvari and Modares Hospital for Coronary Artery Bypass Surgery (CABG).
Exclusion Criteria
History of any allergies to any of the compounds in acetazolamide tablets and sulfonamide compounds
Liver failure (stage II, III or liver enzymes more than 3 times)
Chronic renal failure (Stage IV & V CKD) or patients with serum creatinine less than 30 ml / min, anorexia
Chronic heart failure (Ejection Fraction <30)
Patients undergoing CABG surgery for emergency reasons.
Hypokalemia (potassium less than 3.3 mmol / L), hyponatremia (sodium less than 135 mmol / L)
Gout attack
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Creatinine plasma LEVEL. Timepoint: Before surgery and daily for up to seven days. Method of measurement: ELISA.;Volume of urine. Timepoint: Before the operation until the patient is in the intensive care unit. Method of measurement: The amount of urine in the urine bag.
- Secondary Outcome Measures
Name Time Method