The effect of dietary phosphorus reduction on urine protein excretio

Not Applicable

• Conditions: Proteinuria.; Persistent proteinuria, unspecified

• Registration Number: IRCT20120718010333N4
• Lead Sponsor: Kashan University of Medical Sciences

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 29 January 2019

Recruitment & Eligibility

• Status: Pending
• Sex: All
• Target Recruitment: 90

Inclusion Criteria

Patients with proteinuria in whom the ratio of protein to creatinine in a sample of urine is greater than 0.3 mg/mg
The glomerular filtration rate (eGFR) should be greater than 15 mL/min/1.73 m2
The systolic blood pressure should be less than 150 mmHg
The serum level of phosphorus should be more than 3 mg/dL
Dietary intake of phosphorus should be more than 17-20 mg/kg/day
Patients in whom at least 3 months have passed from the onset of anti-proteinuric medications use
Patients with proteinuria and diabetes in whom at least 3 months have passed from the onset of taking the glucose lowering drugs or insulin
The amount of medications consumed should be constant within 3 months before the start of the study and their type and dosage do not change during the intervention

Exclusion Criteria

Pregnancy
Lactation
Patients with urinary tract infections
Patients with pyelonephritis
Patients with kidney stones
consumption of various kind of phosphate binders
Taking calcium and vitamin D supplements within 3 months before the start of the study

Study & Design

• Study Type: interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
A change in urine protein to creatinine ratio. Timepoint: At baseline and 8 weeks after the start of the phosphorus restricted diet or control diet. Method of measurement: Laboratory clinical kit and analyzer instrument.