MedPath

Study of Travatan and Cosopt in Primary Open-Angle Glaucoma or Ocular Hypertension

Phase 4
Terminated
Conditions
Open-angle Glaucoma
Ocular Hypertension
Interventions
Drug: Placebo (Timolol Vehicle)
Registration Number
NCT00471068
Lead Sponsor
Alcon Research
Brief Summary

To compare the efficacy and safety in patients treated with travoprost versus dorzolamide/timolol maleate combination in patients with open-angle glaucoma or ocular hypertension

Detailed Description

Not available

Recruitment & Eligibility

Status
TERMINATED
Sex
All
Target Recruitment
46
Inclusion Criteria
  • Patient with open-angle glaucoma or ocular hypertension
Exclusion Criteria
  • By Age

Study & Design

Study Type
INTERVENTIONAL
Study Design
PARALLEL
Arm && Interventions
GroupInterventionDescription
TravatanTravatanTravatan: 6 weeks treatment with Travatan (travoprost 40 mg/ml eye drops, solution) once daily at 08:00 and placebo (timolol vehicle) once daily at 20:00 in the affected eye(s)
TravatanPlacebo (Timolol Vehicle)Travatan: 6 weeks treatment with Travatan (travoprost 40 mg/ml eye drops, solution) once daily at 08:00 and placebo (timolol vehicle) once daily at 20:00 in the affected eye(s)
CosoptCosopttreatment period of 6 weeks with Cosopt (dorzolamide 20 mg/ml and timolol maleate 5 mg/ml eye drops, solution) twice daily at 08:00 and 20:00 in the affected eye(s)
Primary Outcome Measures
NameTimeMethod
Intaocular Pressure (IOP) Mean Change After 6 Weeks of TreatmentAt week 0 and week 6

IOP measured at week 6 minus IOP measured at baseline

Secondary Outcome Measures
NameTimeMethod

Trial Locations

Locations (1)

Coimbra

🇵🇹

Coimbra, Portugal

© Copyright 2025. All Rights Reserved by MedPath