Travoprost

Generic Name
Travoprost
Brand Names
Duotrav, Izba, Travatan
Drug Type
Small Molecule
Chemical Formula
C26H35F3O6
CAS Number
157283-68-6
Unique Ingredient Identifier
WJ68R08KX9
Background

Travoprost ophthalmic solution is a topical medication used for controlling the progression of glaucoma or ocular hypertension, by reducing intraocular pressure . It is a synthetic prostaglandin F2alpha analog . Having been a well-received therapeutic agent with demonstrated efficacy and safety, travoprost is currently approved by the US FDA as a first-line ...

Indication

Travoprost ophthalmic solution is indicated for the reduction of elevated intraocular pressure in patients with open-angle glaucoma or ocular hypertension .

Travoprost is also currently indicated for the decrease of elevated intraocular pressure in paediatric patients aged 2 months to < 18 years with ocular hypertension or paediatric glaucoma .

Associated Conditions
Increased Intra Ocular Pressure (IOP)
Associated Therapies
-

Study of Exchange of Travoprost Intraocular Implant

Phase 2
Completed
Conditions
Interventions
First Posted Date
2020-11-04
Last Posted Date
2023-09-26
Lead Sponsor
Glaukos Corporation
Target Recruit Count
33
Registration Number
NCT04615403
Locations
🇺🇸

The Eye Associates of Manatee, Manatee, Florida, United States

🇺🇸

North Bath Eye Associates, Inc., Petaluma, California, United States

🇺🇸

Center for Sight, Sarasota, Florida, United States

and more 11 locations

Phase 3 Study Evaluating Safety and Efficacy of OTX-TP in Subjects With OAG or OHT

First Posted Date
2016-09-26
Last Posted Date
2021-10-11
Lead Sponsor
Ocular Therapeutix, Inc.
Target Recruit Count
565
Registration Number
NCT02914509

Stop Retinal Ganglion Cell Dysfunction Study

First Posted Date
2015-03-17
Last Posted Date
2024-10-10
Lead Sponsor
University of Miami
Target Recruit Count
500
Registration Number
NCT02390284
Locations
🇺🇸

Bascom Palmer Eye Institute - University of Miami, Miami, Florida, United States

Effect of Selective Laser Trabeculoplasty Versus Travoprost on Circardian Intraocular Pressure

First Posted Date
2014-04-07
Last Posted Date
2016-08-08
Lead Sponsor
Prince of Songkla University
Target Recruit Count
60
Registration Number
NCT02105311
Locations
🇹🇭

Songklanagarind Hospital, Hatyai, Songkhla, Thailand

Effect of Travoprost 0.004% on Retinal Oximetry in Primary Open Angle Glaucoma

Not Applicable
Completed
Conditions
Interventions
First Posted Date
2012-10-22
Last Posted Date
2016-07-28
Lead Sponsor
Université de Montréal
Target Recruit Count
14
Registration Number
NCT01711177
Locations
🇨🇦

University of Montreal, Montreal, Quebec, Canada

24-hour Control of Intraocular Pressure (IOP) in Ocular Hypertension

First Posted Date
2012-08-02
Last Posted Date
2012-08-02
Lead Sponsor
University of Parma
Target Recruit Count
61
Registration Number
NCT01655758
Locations
🇮🇹

University Eye Clinic, Parma, Italy

Subjects With Open-angle Glaucoma, Pseudoexfoliative Glaucoma, or Ocular Hypertension Naïve to Medical and Surgical Therapy, Treated With Two Trabecular Micro-bypass Stents (iStent Inject) or Travoprost

Phase 4
Completed
Conditions
Interventions
First Posted Date
2011-09-30
Last Posted Date
2022-09-08
Lead Sponsor
Glaukos Corporation
Target Recruit Count
196
Registration Number
NCT01444040
Locations
🇦🇲

S.V. Malayan Ophthalmological Center, Yerevan, Armenia

Subjects With Open-angle Glaucoma, Pseudoexfoliative Glaucoma, or Ocular Hypertension Naïve to Medical and Surgical Therapy, Treated With Two Trabecular Micro-bypass Stents (iStent)or Travoprost

Phase 4
Completed
Conditions
Interventions
First Posted Date
2011-09-30
Last Posted Date
2017-12-18
Lead Sponsor
Glaukos Corporation
Target Recruit Count
101
Registration Number
NCT01443988
Locations
🇦🇲

S.V. Malayan Ophthalmological Center, Yerevan, Armenia

Effects of Anti-Glaucoma Medications on the Ocular Surface

Phase 4
Terminated
Conditions
Interventions
First Posted Date
2011-03-15
Last Posted Date
2017-03-16
Lead Sponsor
Massachusetts Eye and Ear Infirmary
Target Recruit Count
14
Registration Number
NCT01315574
Locations
🇺🇸

Massachusetts Eye and Ear Infirmary, Boston, Massachusetts, United States

The Effects of Xalatan, Travatan and Lumigan on Skin Pigmentation Near the Eye

First Posted Date
2008-06-26
Last Posted Date
2016-01-18
Lead Sponsor
Summa Health System
Target Recruit Count
89
Registration Number
NCT00705757
Locations
🇺🇸

Arlington Eye Physicians, Arlington Heights, Illinois, United States

🇺🇸

Summa Health System, Akron, Ohio, United States

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