ISRCTN48521078Completed未知
Stress enhances retrieval of heroin-related memories through concurrent effect on glucocorticoids and norepinephrine in abstinent heroin addicts
The National Basic Research Program of China (973 Program) (China)0 sites102 target enrollmentStarted: January 23, 2009Last updated:
Conditions
Trial Snapshot
- Phase
- 未知
- Status
- Completed
- Sponsor
- Enrollment
- 102
Study Overview
Brief Summary
2010 results in: https://www.ncbi.nlm.nih.gov/pubmed/19890257 (added 04/07/2019)
Study Design
- Study Type
- Interventional
Eligibility Criteria
- Sex
- Male
Inclusion Criteria
- •1. Aged from 20 to 40 years, male only
- •2. Diagnostic and Statistical Manual of Mental Disorders, fourth edition (DSM-IV) criteria for heroin dependence with opiate free for at least one month
- •3. No use of other drugs
Exclusion Criteria
- •1. Current use of any medications
- •2. Current DSM-IV diagnosis of any affective, anxiety, or psychotic disorder
- •3. Current dependence on any substance besides heroin and nicotine (based on DSM-IV criteria)
- •4. Risk factors for untoward side effects from propranolol and cortisol (i.e., irregular heartbeats, history of cardiogenic shock, history of severe heart failure, asthma, fungal infections, hyperlipidaemia, history of hypertension, or abnormal electrocardiogram [ECG] or other laboratory findings)
Investigators
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