Sonophoresis in the treatment of periodontitis.

Phase 3

Not yet recruiting

Conditions: Chronic periodontitis, (2) ICD-10 Condition: R898||Other abnormal findings in specimens from other organs, systems and tissues,

Registration Number: CTRI/2020/04/024565

Lead Sponsor: Dipika Inbasekaran

Brief Summary: Periodontitis is a chronic inflammatory disease of multi factorial origin. 50 to 90% of adult population is affected by it, if untreated results in tooth loss. Non surgical periodontal therapy which involves scaling and root planing is considered as gold standard for the management of periodontal diseases. In the past many treatment modalities have been tried as an adjunct to non surgical periodontitis.

Sonophoresis is the use of therapeutic ultra sound in trans dermal drug delivery. It is commonly used in physiotherapy for the management of chronic inflammatory conditions. However, its application in dentistry is limited to the management of tempero mandibular joint disorders. This study aims to asses the role of sonophoresis as an adjunct to non surgical periodontal therapy.

Detailed Description: Not available

Recruitment & Eligibility

Status: Not Yet Recruiting

Sex: All

Target Recruitment: 21

Inclusion Criteria

Chronic periodontitis (AAP 1999 classification) Probing depth of 5mm or more in more than 30% sites Systemically healthy No antibiotic useage in the last 6 months Did not undergo periodontal therapy in the last 6 months Non-pregnant, not lactating women.

Exclusion Criteria

Patients with systemic diseases Patients allergic to metronidazole.

Study & Design

Study Type: Interventional

Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Periodontal probing depth in mm, MMP-8 levels in saliva using ELISA, bacterial colony forming units (CFU)	baseline, 1 month post treatment

Secondary Outcome Measures

Name	Time	Method
Clinical attachment level	Baseline, 1 month post treatment
Plaque index	Baseline and 1 month post treatment
Bleeding index	Baseline, 1 month post treatment

Trial Locations

Locations (1): Saveetha Dental college
🇮🇳
Chennai, TAMIL NADU, India
Saveetha Dental college
🇮🇳Chennai, TAMIL NADU, India
Dipika Inbasekaran
Principal investigator
8828486379
dipikagopalnambi@gmail.com