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临床试验/CTRI/2024/10/075857
CTRI/2024/10/075857尚未招募不适用

Addition Of Ultrasound Guided Excursion Time Index To Conventional Weaning Criteria Vs Conventional Weaning Criteria Alone For Extubation In ICU Patients -A Comparative Study

Sri Guru Ram Das Institute of Medical Sciences and Research1 个研究点 分布在 1 个国家目标入组 70 人开始时间: 2024年10月30日最近更新:

试验速览

阶段
不适用
状态
尚未招募
发起方
入组人数
70
试验地点
1
主要终点
To assess whether the diaphragm ultrasound based ET index can be used as another parameter for the weaning process

研究概览

简要总结

Introduction: Ventilator weaning is an essential step in the care of ICU patients, involving the gradual removal of mechanical ventilatory support. Determining the correct timing for extubation in mechanically ventilated patients is a significant challenge for intensivists. If USG-guided ETI proves to be superior to conventional weaning criteria, it could enhance patient outcomes by reducing the incidence of failed extubations, minimizing the need for reintubation, and shortening ICU length of stay. Therefore, comparing these two approaches is crucial for advancing our understanding of extubation readiness and optimizing the care of ICU patients undergoing mechanical ventilation.

Aims and Objectives: Aim of the study is to Compare USG guided excursion time index alongwith conventional weaning criteria for successful extubation in ICU patients. Objective of the study is to determine if USG-guided excursion time index can aid in successful ICU weaning and to compare extubation success rates using this index alongside conventional weaning criteria versus conventional criteria alone.

Methodology: The study is proposed to be conducted from July 2024 to December 2025 at the Department of Anaesthesiology and Critical Care, Sri Guru Ram Das Institute of Medical Sciences & Research, Amritsar. It will focus on critically ill patients undergoing mechanical ventilation and supposed ready for weaning in the intensive care unit. Mechanically ventilated patients will be randomly divided into two groups. Group A will be extubated using conventional weaning criteria and Group B will be extubated using conventional weaning criteria along with USG guided excursion time index.

Outcome/Significance:. Both groups will be compared for extubation success and extubation failure, defined as patients reintubated within 48 hours. Primary Outcome of the study will be to assess whether the diaphragm ultrasound-based ETI can be used as an additional parameter in the weaning process.

研究设计

研究类型
Interventional
分配方式
Randomized
盲法
None

入排标准

年龄范围
18.00 Year(s) 至 80.00 Year(s)(—)
性别
All

入选标准

  • Age more than 18 years.

排除标准

  • Pregnant women
  • Patients with Neuromuscular disorders
  • Diaphragm paralysis
  • Pneumothorax
  • Massive pleural effusion
  • Tracheostomised.

结局指标

主要结局

To assess whether the diaphragm ultrasound based ET index can be used as another parameter for the weaning process

时间窗: from the time when patients needs extubation till 72 hours post extubation

次要结局

  • 1. Role of ultrasound guided diaphragm function for weaning outcome.(2. To compare APACHE II score with number of days a patient is ventilated.)

研究者

发起方
Sri Guru Ram Das Institute of Medical Sciences and Research
申办方类型
Research institution and hospital
责任方
Principal Investigator
主要研究者

Dr Sunil Chawla

Sri Guru Ram Das Institute of Medical Sciences and Research

研究点 (1)

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