To compare the bone forming capacity of 1.2% Simvastatin and Rosuvastatin with collagen.
- Conditions
- Health Condition 1: K047- Periapical abscess without sinus
- Registration Number
- CTRI/2022/06/042982
- Lead Sponsor
- ma Bharathy R
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
Patients between 20-40 years of age from both the gender, Periapical lesions involving maxillary and mandibular incisors of strictly endodontic
origin, The diameter of the bone defect of 10 -20 mm, Patients willing for voluntary participation & have signed informed consent, Patients with good oral hygiene, Systemically healthy patients.
Periodontally compromised teeth with poor prognosis, Tooth with pathosis associated with vertical root fracture, Patients with bleeding disorders, Platelet count <1, 50, 000/mm3, Patients showing unacceptable oral hygiene maintenance, Patients with use of tobacco or tobacco related products, Pregnant / Lactating patients, Patients with known systemic diseases, Patients with any known allergies, Patients with any known metabolic disorders.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Absence of swelling, pain, pus discharge, sinus opening, Mobility, Tenderness to percussionTimepoint: 1,3,6,9 and 12 months
- Secondary Outcome Measures
Name Time Method Bone density evaluation of the Periapical region was done after surgery using CBCTTimepoint: 6 and 12 months