NL-OMON25753
Recruiting
N/A
Chemoradiation followed by surgery for patients with cT4 oesophageal carcinoma.
Academic Medical Center (AMC), Department of Surgery0 sites30 target enrollmentTBD
Overview
- Phase
- N/A
- Intervention
- Not specified
- Conditions
- Esophageal carcinoma, Esophagectomy, Chemoradiotherapy, T4 tumor
- Sponsor
- Academic Medical Center (AMC), Department of Surgery
- Enrollment
- 30
- Status
- Recruiting
- Last Updated
- 2 years ago
Overview
Brief Summary
/A
Investigators
Eligibility Criteria
Inclusion Criteria
- •1\. Histologically proven squamous cell carcinoma, adenocarcinoma or undifferentiated carcinoma of the intrathoracic esophagus or gastroesophageal junction;
- •2\. Surgically irresectable T4 carcinoma as determined by endoscopic ultrasonography (EUS), CT scan or PET\-CT of neck, thorax and abdomen, without distant mestastases.
Exclusion Criteria
- •1\. cT4 carcinoma with tracheobronchial involvement demonstrated on bronchoscopy after chemoradiotherapy;
- •2\. Past or current history of malignancy other than entry diagnosis except for non\-melanomatous skin cancer, or curatively treated in situ carcinoma of the cervix, or malignancy more than 5 years prior to enrollment;
Outcomes
Primary Outcomes
Not specified
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