The Treatment Effect of Nonsurgical Periodontal Therapy for Eradication of Helicobacter Pylori Infection Following Systemic Therapy

Not Applicable

Recruiting

• Conditions: Peptic ulcer or dyspepsia.; Acute peptic ulcer

• Registration Number: IRCT20110109005570N9
• Lead Sponsor: Vice chancellor For Research Of Isfahan University Of Medical Sciences

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Last Update Posted: 26 April 2021

Recruitment & Eligibility

• Status: Recruiting
• Sex: All
• Target Recruitment: 75

Inclusion Criteria

Peptic ulcer or dyspepsia positive for helicobacter pylori infection based on stool helicobacter pylori antigen test evaluation or serology

Exclusion Criteria

Suffering from MALT
Zolinger Elison syndrome
GI tract cancer
Liver and kidney disease
Tacking antibiotics or probiotic in past 4 weeks or any contraindication for tacking medicinal diet
Immunologic disease
Pregnancy
History of upper GI tract surgery
History of eradication of Helicobacter pylori infection
History of tacking PPI
Do not take medication regularly(20% or more)
Serious side effect as a result of tacking medication
Request a patient to leave the study
Failure for oral hygiene.

Study & Design

• Study Type: interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
The presence of H. pylori in GI tract and its eradication. Timepoint: Base line(before treatment), 1 months after treatment. Method of measurement: Stool H. pylori antigen test.;Presence of H. pylori in dental plaque. Timepoint: Base line(before treatment). Method of measurement: Rapid Urease Test.

Secondary Outcome Measures

Name	Time	Method
Probing depth. Timepoint: Base line(before treatment),1 months after treatment. Method of measurement: Probing by Williams prob, from gingival margin to depth of pocket.;Plaque index. Timepoint: Base line(before treatment) and 1 months after treatment. Method of measurement: Plaque index of silness and loe.