Efficacy of internal use of Apamarga kshara in the management of mutrashmari with special reference to nephrolithiasis
试验速览
- 阶段
- 3 期
- 状态
- 尚未招募
- 发起方
- 入组人数
- 30
- 试验地点
- 1
- 主要终点
- The internal use of apamarga kshara may show improvements
研究概览
简要总结
Mutrashmari or urinary stone is the most painful & common disease of the urinary system in human beings. It is the third most common affliction of the urinary tract, exceeded only by UTI and BPH. As per classics Ashmari is included in Ashta mahagada due to its fatal nature. Total 30 patients will be selected and whole sample will be given Apamarga
Khsara capsule 500mg twice daily orally for 45 days.
The most common presenting symptoms of nephrolithiasis are sudden-onset, flank pain, haematuria, nausea, and vomiting. The pain waxes and wanes in the acute phase and patients are often unable to find a comfortable position and appear writhing in pain.
In the present study, Apamarga Paniya Kshara will be used as a remedy in Mutrashmari and have Lekhana(scraping) and Bhedana (cutting) properties, so these are more suitable for Mutrashmari as they help to expel out the Mutrashmari by reducing its size. Necessary assessment parameter will be used here and final assessment and conclusion may be made through statistical analysis.
The conclusions will be drawn on the basis of findings at the end of the study by evaluating the findings of subjective and objective parameters.
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 盲法
- None
入排标准
- 年龄范围
- 18.00 Year(s) 至 60.00 Year(s)（—）
- 性别
- All
入选标准
- •Patients between 18 to 60 years of age group Patients with clinical signs and symptoms of Mutrashmari as mentioned in classical Ayurvedic texts and modern literature.
- •Size of calculus less than 10 mm Patient will be selected irrespective of caste and religion.
- •Patient willing for the trial.
排除标准
- •Patients below 18 years and above 60 years.
- •Size of calculus more than 10mm.
- •Patient with acute pain.
- •Chronic kidney disease.
- •Hydronephrosis.
- •Pyelonephritis.
- •Uncontrolled diabetes mellitus.
- •Uncontrolled hypertension.
- •Lactating or any pregnancy in females.
- •Patients undergoing hormonal therapy.
- •Any malignancy.
- •Any cardiac disease.
结局指标
主要结局
The internal use of apamarga kshara may show improvements
时间窗: 0TH DAY, 15TH DAY, 30TH DAY, 45TH DAY
in subjective symptoms such as Pain in abdomen, renal angle, radiating to groin,Haematuria, Burning micturition.
时间窗: 0TH DAY, 15TH DAY, 30TH DAY, 45TH DAY
Frequency of micturition.
时间窗: 0TH DAY, 15TH DAY, 30TH DAY, 45TH DAY
Associated symptoms fever, nausea, vomiting of mutrashmari
时间窗: 0TH DAY, 15TH DAY, 30TH DAY, 45TH DAY
次要结局
- Inter al use(The internal use of apamarga kshara may show improvements)
研究者
Dr Subir Kumar Khan
The West Bengal University of Health Sciences