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Clinical Trials/NCT06239571
NCT06239571
Active, Not Recruiting
N/A

Resilient Families: A Dyadic Resiliency Intervention for Parents of Babies in the NICU

Massachusetts General Hospital1 site in 1 country10 target enrollmentMay 8, 2025
ConditionsParents

Overview

Phase
N/A
Intervention
Resilient Families (R-FAM)
Conditions
Parents
Sponsor
Massachusetts General Hospital
Enrollment
10
Locations
1
Primary Endpoint
Depression
Status
Active, Not Recruiting
Last Updated
3 months ago

Overview

Brief Summary

The goal is to develop, refine, and test the feasibility and acceptability of a dyadic, resiliency intervention ("Resilient Families;" R-FAM) that aims to reduce emotional distress and improve relationships among parents in the Neonatal Intensive Care Unit (NICU). To achieve this goal, my aims are three-fold: (1) develop R-FAM using stakeholder input from interviews with parent dyads and focus groups with NICU staff; (2) optimize R-FAM through an open pilot with pre/post assessments and exit interviews; and (3) test R-FAM for feasibility and acceptability through a randomized clinical trial of R-FAM compared with a minimally enhanced usual control (MEUC).

Detailed Description

The investigators aim to conduct an open pilot trial of the R-FAM program (Resilient Families) with NICU parents (up to N = 6 dyads) followed by an optional brief exit interview. The investigators will determine if the feasibility, acceptability, and fidelity of the program meet a priori benchmarks. The investigators also hope to establish preliminary efficacy that the program reduces parental emotional distress and other study outcomes described in sections below. The investigators will use qualitative data to optimize the intervention and study procedures for future trials. This Open Pilot trial will include 6 sessions with a clinical psychologist. The intervention will aim to improve coping skills, communication, and stress management. Participants will learn evidence-based skills (e.g., mindfulness, dialectics, problem-solving) to reduce risk for emotional distress. The primary outcomes for the open pilot will be the feasibility, acceptability, and fidelity of the R-FAM program. Preliminary effectiveness outcomes will also be examined, as in primary and secondary targets and exploratory outcomes (e.g., emotional distress, couple satisfaction, and family impact).

Registry
clinicaltrials.gov
Start Date
May 8, 2025
End Date
March 31, 2028
Last Updated
3 months ago
Study Type
Interventional
Study Design
Single Group
Sex
All

Investigators

Responsible Party
Principal Investigator
Principal Investigator

Victoria A. Grunberg, PhD

Clinical Psychologist

Massachusetts General Hospital

Eligibility Criteria

Inclusion Criteria

  • Adult parent/legal guardian (and/or their partner) of a baby admitted to the NICU within past week (age ≥ 18)
  • Currently in an intimate relationship and will live with baby after NICU discharge
  • At least one dyad member is emotionally distressed (HADS \>7 on depression or anxiety subscale)
  • English fluency/literacy
  • Ability and willingness to participate via live video

Exclusion Criteria

  • Baby is expected to pass away (as determined by medical team)
  • Current, untreated psychosis or substance dependence/abuse
  • Current self-report of suicidal ideation

Arms & Interventions

Dyadic Resiliency Intervention

All participants will receive the intervention, a brief dyadic resiliency intervention

Intervention: Resilient Families (R-FAM)

Outcomes

Primary Outcomes

Depression

Time Frame: Baseline to end of intervention (6 weeks)

Level of depression endorsed on Hospital Anxiety \& Depression Scale and Edinburgh Postnatal Depression Scale, from 0-30 with 30 indicating highest depression

Anxiety

Time Frame: Baseline to end of intervention (6 weeks)

Level of anxiety endorsed on Hospital Anxiety \& Depression Scale, from 0-21 with 21 indicating highest anxiety

Posttraumatic Stress

Time Frame: Baseline to end of intervention (6 weeks)

Level of posttraumatic stress endorsed on Impact of Event Scale-6, from 6-24 with 24 indicating highest posttraumatic stress

Secondary Outcomes

  • Couple relationship functioning(Baseline to end of intervention (6 weeks))
  • Family Impact(Baseline to end of intervention (6 weeks))

Study Sites (1)

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