The Effect of Exercise Intervention on the Physical Fitness, Bone Mineral Density and Health-related Quality of Life in the Community's Older Adults
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 411
- 试验地点
- 2
- 主要终点
- Change from baseline bone mineral density
研究概览
简要总结
Osteoporosis is a serious global health problem, second only to cardiovascular disease. Osteoporosis is the most common metabolic bone disease in the elderly population, characterized by loss of bone mineral density (BMD) and continuous destruction of bone microstructure, especially in postmenopausal women. It gives rise to bone fragility and fracture risk. Moreover, as people grow older, falls frequently occur with high severity, and nearly 35% to 45% of persons aged 65 or older fall at least once a year. Osteoporotic fractures increase mortality, morbidity, chronic pain, and the cost of social care and it decreases the quality of life. Here, investigators plan to perform different exercise interventions such as circuit exercise, aerobic dance and Tai Chi on the community's older adults to evaluate whether exercise intervention could improve the bone mineral density, physical fitness, muscle strength or quality of life.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Basic Science
- 盲法
- Double (Participant, Outcomes Assessor)
入排标准
- 年龄范围
- 45 Years 至 85 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Being >45 years-of-age,
- •Healthy and physically independent.
排除标准
- •The exclusion criteria were individuals on hormone replacement therapy and those with cognitive impairment, progressive debilitating conditions, bone fractures, or any medical contraindications to administering the fitness assessment.
研究组 & 干预措施
Control
without exercise intervention
Exercise
Subjects with circuit exercise, aerobic dance, or Tai Chi exercise intervention.
干预措施: exercise (Other)
结局指标
主要结局
Change from baseline bone mineral density
时间窗: Pre-intervention, 3-month, 6-month, 9-month-follow-up
Bone mineral density measurement is measured by dual-energy x-ray absorptiometry (DXA). Measurements are made over the lumbar spine and over the upper part of the hip and the measurement is assessed at Pre-intervention, 3-month, 6-month, 9-month-follow-up.
次要结局
- Triglyceride from blood sample(Pre-intervention, 3-month, 6-month, 9-month-follow-up)
- Waistline parameters of the subjects(Pre-intervention, 3-month, 6-month, 9-month-follow-up)
- Change from baseline elbow muscle strength(Pre-intervention, 3-month, 6-month, 9-month-follow-up)
- High-density lipoprotein from blood sample(Pre-intervention, 3-month, 6-month, 9-month-follow-up)
- Change from baseline shoulder muscle strength(Pre-intervention, 3-month, 6-month, 9-month-follow-up)
- Change from baseline hip muscle strength(Pre-intervention, 3-month, 6-month, 9-month-follow-up)
- Fasting blood glucose from blood sample(Pre-intervention, 3-month, 6-month, 9-month-follow-up)
- Blood pressure(Pre-intervention, 3-month, 6-month, 9-month-follow-up)
- Weight parameters of the subjects(Pre-intervention, 3-month, 6-month, 9-month-follow-up)
- Height parameters of the subjects(Pre-intervention, 3-month, 6-month, 9-month-follow-up)
- Change from baseline knee muscle strength(Pre-intervention, 3-month, 6-month, 9-month-follow-up)
- Change from baseline SF-36 questionnaire assessment(Pre-intervention, 3-month, 6-month, 9-month-follow-up)
研究者
Robert Wen-Wei Hsu
Honorary Dean
Chang Gung Memorial Hospital