Impact of "ASAP" Multidisciplinary Optimization Care Protocol on Clinical Outcome in Elderly Inpatients for Hip Fracture

Completed

• Conditions: Hip Fractures
• Interventions: Other: ASAP care's protocol

• Registration Number: NCT04771364
• Lead Sponsor: University of Liege

Brief Summary

To compare the impact of ASAP protocol (geriatric advice, early surgery, loco-regional anesthesia and pharmacological adaptation) on elderly patients with hip fracture and clinical outcome.

Detailed Description

Retrospective double cohort analysis for ASA physical status 1, 2 and 3 elderly patients \>65 years old, scheduled to undergo surgery for hip fracture between January 1st 2017 and December 31st 2022.

The investigator want to confirm the better outcome on 30-days mortality after surgery in patients where the ASAP protocol was applied, starting from 1 January 2020.

ASAP protocol follow the latest international guidelines about hip fracture in elderly patient. The investigator focuses the research about the impact of ASAP protocol on clinical outcome: geriatrician's advice, impact of loco-regional techniques on intra-operative and postoperative pain control, chronic pharmacological therapy's adaptation and 30-days postoperative mortality.

Study Timeline

• Study Start: 2017-01-01
• Study First Submitted: 2021-02-22
• Study First Submitted QC: 2021-02-22
• Study First Posted: 2021-02-25
• Primary Completion: 2022-12-31
• Study Completion: 2022-12-31
• Status Verified: 2023-01
• Last Update Submitted: 2023-01-06
• Last Update Posted: 2023-01-10

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 800

Inclusion Criteria

• Over 65 years old patients with hip fractures between January 1st 2017 and December 31th 2022

Exclusion Criteria

• Fracture without indication for surgery
• Death before surgery
• Intensive care's or polytrauma patients (> 2 fracture sites) or under pharmacological coma needed before and after surgery.

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Arm && Interventions

Group	Intervention	Description
ASAP cohort	ASAP care's protocol	Patients aged \>65 years old scheduled for hip fracture between January 1st 2020 and December 31th 2022. Standard anesthesiology cares were performed, as usual in our hospital institution, but the investigator focused the attention on these cares' adaptation: early geriatrician's advice, prefer locoregional anesthesia techniques where possible, early surgical therapy and medical adaptation on chronic therapy.

Primary Outcome Measures

Name	Time	Method
Postoperative complications	7 days	Neurological, cardiovascular, pulmonary, renal, infectious and gastrointestinal complications after surgery.

Secondary Outcome Measures

Name	Time	Method
Days of hospitalisation	30 days	Total hospitalisation days
30-days postoperative mortality	30 days	Mortality 1 month after surgery

Trial Locations

Locations (1)

CHU de Liège; 🇧🇪 Liège, Belgium