Maternal Serum Amyloid A Levels in Pregnancies Complicated With Preterm Labour.

• Conditions: Preterm Labor

• Registration Number: NCT03205020
• Lead Sponsor: mona nematallah

Brief Summary

The aim of the current study is to assess the accuracy of maternal serum amyloid A for prediction of preterm labor in women with threatened preterm labor.

Detailed Description

Not available

Study Timeline

• Status Verified: 2017-06
• Study First Submitted: 2017-06-13
• Study First Submitted QC: 2017-06-28
• Last Update Submitted: 2017-06-30
• Study Start: 2017-07-01
• Study First Posted: 2017-07-02
• Last Update Posted: 2017-07-05
• Primary Completion: 2018-01-01
• Study Completion: 2018-02-01

Recruitment & Eligibility

• Status: UNKNOWN
• Sex: Female
• Target Recruitment: 58

Inclusion Criteria

• Pregnant women, age 18 - 35.
• Gestational age: 28 - 36+6 weeks.
• Singleton pregnancy.
• No past history of any medical disorder and with no other medical complications during pregnancy
• Nonsmoker.
• Diagnosis of preterm labor is based on the American College of Obstetricians and Gynecologists Guidelines

Criteria of preterm delivery:

1. Gestational age: 28 - 36+6 weeks
2. Presence of uterine contractions (at least 4 in 20 minutes or 8 in 60 minutes)
3. cervical dilation ≥ 4 cm
4. Cervical effacement ≥ 80%.

Exclusion Criteria

• Of any patient with the following risk factors for preterm labor:

  • Over distended uterus .
  • hemorrhage
  • Uterine anomalies

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
prevalence of Amyloid A level in women with preterm labour	6 months	venous sample will be taken from each participant from onset of labour, Amyloid a level will be calculated

Secondary Outcome Measures

Name	Time	Method
neonatal complications	6 months	preterm baby will be examined at neonatal intensive care unit by neonatologist.; • Admission to Neonates intensive care unit.

Trial Locations

Locations (1)

Ain Shams University; 🇪🇬 Cairo, Egypt