Continuation of platelet inhibiting drugs in eyelid surgery. A randomized, double-masked, placebo-controlled clinical trial.

Phase 4

Completed

• Conditions: bleeding; haemorrhagic complications in oculoplastic surgery; 10015917; 10015957

• Registration Number: NL-OMON33474
• Lead Sponsor: Oogziekenhuis Rotterdam

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Last Update Posted: 6 May 2024

Recruitment & Eligibility

• Status: Completed
• Sex: Not specified
• Target Recruitment: 324

Inclusion Criteria

daily use of acetylsalicylic acid or carbasalate calcium
scheduled for surgical correction of ectropion or entropion, or for non-cosmetic upperlid blepharoplasty without fat excision

Exclusion Criteria

concomitant use of other anticoagulant drugs (coumarin derivatives, clopidogrel, dipyridamol, NSAIDs)
known systemic disease that affects haemostasis
prescribing physician advising against discontinuation
obvious fat prolapses that need to be excised in case of blepharoplasty.
general anaesthesia

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<p>Peroperative bleeding<br /><br>Postoperative bleeding<br /><br>Postoperative bruising </p><br>

Secondary Outcome Measures

Name	Time	Method
<p>Retrobulbar haemorrhage<br /><br>Result of surgery<br /><br>Duration of surgery<br /><br>Cardiac or cerebral ischaemic event</p><br>