Mesenteric Panniculitis : Review of Consecutive Abdominal MDCT Examinations With a Matched-pair Analysis

Completed

• Conditions: Mesenteric Panniculitis
• Interventions: Other: Review of multidetector row computed tomography scans

• Registration Number: NCT03316001
• Lead Sponsor: CHU de Reims

Brief Summary

Mesenteric panniculitis is a benign inflammatory condition that involves the adipose tissue of the intestinal mesentery. Clinical manifestations are uncommon, non specific and atypical. Mesenteric panniculitis is thus most often an incidental finding during an investigation for other reason, mostly on computed tomography scans. The rate of malignancy in patients with mesenteric panniculitis, especially urogenital and gastrointestinal adenocarcinomas or lymphomas, has been reported to be as high, thus suggesting that there may be a relationship between mesenteric panniculitis and progression of an underlying malignancy or the risk of a future malignancy.

Detailed Description

The aim was:

to estimate the prevalence of mesenteric panniculitis. to study relationship between mesenteric panniculitis and malignancy. to investigate the 5-year outcome of patients with mesenteric panniculitis for the development of malignancy.

Study Timeline

• Study Start: 2014-11
• Primary Completion: 2015-03
• Study Completion: 2015-07
• Status Verified: 2017-10
• Study First Submitted: 2017-10-17
• Study First Submitted QC: 2017-10-19
• Last Update Submitted: 2017-10-19
• Study First Posted: 2017-10-20
• Last Update Posted: 2017-10-20

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 288

Inclusion Criteria

Not provided

Exclusion Criteria

Not provided

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Arm && Interventions

Group	Intervention	Description
cases	Review of multidetector row computed tomography scans	patients with a CT scan from January to August 2008 for which mesenteric panniculitis was diagnosed
controls	Review of multidetector row computed tomography scans	patients with a CT scan from January to August 2008 for which mesenteric panniculitis wasn't diagnosed and matched by gender and age with "cases" patients

Primary Outcome Measures

Name	Time	Method
mesenteric panniculitis	Day 0	mesenteric panniculitis is identified on the basis on the presence of three of the following 5 signs on CT scan: * higher attenuation of the fat of the root of the small bowel mesentery,; * a pseudo mass smoothly displacing neighboring structures with a hyperdense pseudocapsule surrounding the mesenteric fat,; * lymph nodes within the fatty pseudo mass and; * a hypodense halo around the nodes and the blood vessels