Improving the response to high intensity interval training through the ingestion of a daily prebiotic fibre.

Not Applicable

Completed

• Conditions: Cardiorespiratory fitness; Diet and Nutrition - Other diet and nutrition disorders; Cardiovascular - Normal development and function of the cardiovascular system

• Registration Number: ACTRN12618000501246
• Lead Sponsor: niversity of Queensland

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2018-04-06
• Study Completion: 2019-08-01
• Last Update Posted: 21 July 2021

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 40

Inclusion Criteria

•Inactive adults aged between 18 and 50 years
•Less than 60 minutes of structured exercise each week
•Signed consent form

Exclusion Criteria

•Antibiotic use 6 months prior to intervention or antibiotic use during intervention.
•Pre- or-probiotic use within four weeks of participating in study
•Pregnancy, chronic infections, auto-immune diseases and intestinal chronic conditions (e.g. IBS, Chrohn’s disease, ulcerative colitis, coeliac disease).
•Existing cardiac conditions
•Recent surgery or orthopaedic conditions that prevents treadmill walking/running

•Diabetes
•Allergies to inulin (chicory root) or fructans
•Allergies to maltodextrin and other polysaccharides
•Allergies to soy, milk and egg (there maybe traces of these in maltodextrin)
•Greater than 60 minutes of exercise per week within four weeks of the study

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
An incremental treadmill test to exhaustion will be completed to ascertain VO2peak. This test will be the Bruce Ramp protocol. This test will be assessed via indirect calorimetry and will determine VO2peak directly.[Pre and post 6 week exercise intervention (8 weeks post randomisation).];A panel of genetic variants that are correlated with VO2peak training reponse will be identified from a saliva sample collected via an Oragene collection kit. Saliva samples will be sent to the Translational Research Institute (TRI) for DNA extraction and GWAS analysis. [Baseline]