Comparison of the effects of the two drugs dexmedetomidine and midazolam when given for spinal anaesthesia
- Conditions
- Patients with major co-morbid conditions
- Registration Number
- CTRI/2018/03/012353
- Lead Sponsor
- Dr J Jancy
- Brief Summary
Spinal anaesthesia is the commonly employed anaesthetic technique for lower limb surgeries. But it’s limitation is short duration of analgeisa. In order to extended the duration of block a number of agents are added along with local anaesthetic for spinal anaesthesia. Dexmedetomidine and midazolam are two such additives for spinal anaesthesia. In the present study we intend to compare dexmedetomidine and midazolam when added to spinal anaesthesia with 0.75% ropivacaine spinal anaesthesia.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Not Yet Recruiting
- Sex
- All
- Target Recruitment
- 88
- 1)Age 18-60 years.
- 2)American Society of Anaesthesiologists (ASA) Grade I and II.
1)Patient refusal for subarachnoid block 2)Known allergy to the study drugs 3)Infection at the puncture site 4)Coagulation disorders 5)Neurological disorders 6)Hepatic and renal disorders 7)Use of antipsychotic medications 8)Body mass index ≥ 30kg/m2 9)Pregnancy & lactation 10)ASA ≥ III.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Onset and duration of sensory and motor block 1)Onset of motor and sensory block will be assessed every 3min for the first 15 min after spinal anaesthesia. | 2) Duration of motor and sensory block will be assessed at the end of surgery in the post operative period.
- Secondary Outcome Measures
Name Time Method Haemodynamic stability Duration of analgesia
Trial Locations
- Locations (1)
Ramaiah Medical College Hospital
🇮🇳Bangalore, KARNATAKA, India
Ramaiah Medical College Hospital🇮🇳Bangalore, KARNATAKA, IndiaDr J JancyPrincipal investigator9080112470jancyjoseph0601@gmail.com