Platelet Inhibition and Bleeding in Patients Undergoing Non-Cardiac Surgery

Completed

• Conditions: Postoperative Bleeding

• Registration Number: NCT01606865
• Lead Sponsor: Medical University of Graz

Brief Summary

The aim of the study is to evaluate if there is an association between platelet inhibition and surgery-related bleeding in patients undergoing non-cardiac surgery during dual antiplatelet therapy.

Detailed Description

Not available

Study Timeline

• Study Start: 2010-09
• Study First Submitted: 2012-05-24
• Study First Submitted QC: 2012-05-25
• Study First Posted: 2012-05-28
• Primary Completion: 2014-01
• Study Completion: 2014-01
• Status Verified: 2014-10
• Last Update Submitted: 2014-10-22
• Last Update Posted: 2014-10-23

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 207

Inclusion Criteria

• intake of Clopidogrel, Prasugrel, or Ticagrelor within the last 7 days
• spontaneous bleeding or impeding surgery (major vascular surgery, intraperitoneal or intrathoracic surgery, ENT-surgery, orthopedic or trauma surgery, prostatic surgery)

Exclusion Criteria

• concomitant medication with warfarin
• renal insufficiency needing dialysis
• concomitant therapy with GPIIB/IIIA Antagonists
• expected duration of operation >30min

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
increased risk of bleeding (according to TIMI definition)	24hours postoperatively

Trial Locations

Locations (1)

Department of Anesthesiology and Intensive Care Medicine, Medical University Graz; 🇦🇹 Graz, Austria