Impact of Gamma Knife Radiosurgery on Tectal Plate Gliomas
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 60
- 试验地点
- 1
- 主要终点
- Incidence of response
研究概览
简要总结
This study aimed to assess the impact of gamma knife radiosurgery on tectal plate gliomas (TPGs).
详细描述
Tectal plate gliomas (TPGs) represent a subset of brainstem gliomas that are predominantly slow-growing, low-grade tumors and rarely produce neurological deficits.
Viable options include biopsy and monitoring with serial neuroimaging, surgical resection, radiotherapy (either early following surgery or late on evidence of disease progression), chemotherapy, and stereotactic radiosurgery (SRS).
SRS using Gamma Knife radiosurgery (GKRS) has been identified in small case series as a safe and promising approach for managing TPGs that necessitate intervention beyond mere observation.
研究设计
- 研究类型
- Observational
- 观察模型
- Other
- 时间视角
- Retrospective
入排标准
- 年龄范围
- 5 Years 至 55 Years（Child, Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Age from 5 to 55 years.
- •Both sexes.
- •Patients underwent gamma knife radiosurgery (GKRS) for tectal plate gliomas (TPGs).
排除标准
- •High-grade glioma.
- •Tumor extension beyond the tectal region.
结局指标
主要结局
Incidence of response
时间窗: One year post-procedure
Incidence of response was recorded.
次要结局
未报告次要终点
研究者
Awad Mohamed Hegab
Lecturer of Neurosurgery, Faculty of Medicine, Al-Azhar University, Damietta, Egypt.
Al-Azhar University