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临床试验/NL-OMON33767
NL-OMON33767已完成不适用

The role of innate immunity and regulatory T cells in the development of immune tolerance in early life. - The development of immunological tolerance in early life

niversitair Medisch Centrum Utrecht0 个研究点目标入组 120 人开始时间: 待定最近更新:
适应症

试验速览

阶段
不适用
状态
已完成
发起方
入组人数
120

研究概览

简要总结

暂无简介。

研究设计

研究类型
Observational

入排标准

年龄范围
2 至 99(—)

入选标准

  • - antanatal diagnosed birthdefect such as schizis, duodenal atresia or orthopedic problems
  • - uncomplicated pregnancy and delivery
  • - birth planned in UMCU/WKZ
  • - a term delivery
  • - availability of cordblood
  • - one or more times surgery in the first year of life

排除标准

  • Complications during pregnancy (HELPP, infection)
  • Use of immune modulating medication during pregnancy
  • Smoking during pregnancy
  • Perinatal complications
  • - Prematurity (<36 weeks) or dysmaturity (birthweight - Use of antibiotics by the mother in the two weeks before delivery
  • - Use of antibiotics by the child in the first two weeks of life
  • - Immunological disorders such as VCF, DiGeorge
  • - Chromosomal disorder
  • - Perinatal infection

研究者

发起方
niversitair Medisch Centrum Utrecht

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