Relationship between the cell free DNA load and response to neoadjuvant chemotherapy in locally advanced breast cancer
Not Applicable
- Conditions
- Health Condition 1: O- Medical and Surgical
- Registration Number
- CTRI/2020/05/025015
- Lead Sponsor
- HCG Hopsital
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
Patient betwee with Locally advanced breast cancer those who are planned NACT followed by surgery [TNM III A&B,C]
Histologically confirmed ca breast and studied for ER/PR/HER2/Ki67
EF >/ 50 those who are receiving anthracycline based chemotherapy
Exclusion Criteria
Metastatic breast cancer ,
Neoadjuvant hormal therapy,
Male breast cancer
Study & Design
- Study Type
- Observational
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Cell free DNA LoadTimepoint: before and after the neo adjuvant chemotherapy
- Secondary Outcome Measures
Name Time Method Radiological and pathological responseTimepoint: during and after the chemotherapy