Colon cancer detection by measuring DNA of cells collected from rectum: A case-control study

Completed

• Conditions: Colorectal cancer; Cancer; Malignant neoplasm of colon

• Registration Number: ISRCTN95403112
• Lead Sponsor: Colonix Medical Ltd (UK)

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2008-07-16
• Last Update Posted: 13 January 2015

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 170

Inclusion Criteria

1. Case group: Consecutive patients (both males and females) with clinical diagnosis of colorectal malignancies recruited by Colorectal Surgery Department of the John Radcliffe Hospital (Oxford, UK)
2. Control group: Clinically healthy volunteers (both males and females), age 50-70, recruited by Honiton Hospital (Honiton, UK)

Exclusion Criteria

1. For both case and control groups: Extensive surgical interventions in the colorectal region or colorectal malignancies in the past
2. For control group: Chronic colorectal conditions (even asymptomatic)

Study & Design

• Study Type: Observational
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
DNA yields from exfoliated materials (DNA scores) are assessed in terms of their predictive value in detecting the presence of colorectal cancer

Secondary Outcome Measures

Name	Time	Method
o secondary outcome measures