Scaling Colorectal cancer screening through Outreach, Referral, and Engagement (SCORE)

Not Applicable

Completed

• Conditions: Colorectal cancer; Cancer

• Registration Number: ISRCTN88368130
• Lead Sponsor: C Lineberger Comprehensive Cancer Center

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2020-06-09
• Study Completion: 2021-12-30
• Last Update Posted: 4 March 2024

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 215

Inclusion Criteria

1. Aged between 50 and 75 years
2. At average risk for colorectal cancer (CRC). Average risk defined as those patients who do not have any of the following: history of CRC, colonic adenomas, Lynch syndrome, family history of CRC, or diagnosis of inflammatory bowel disease.
3. Active patient (seen within the past 18 months) of the community health centers

Exclusion Criteria

1. Record of fecal occult blood test (FOBT)/fecal immunochemical test (FIT) within 12 months or colonoscopy within 10 years, sigmoidoscopy within 5 years, barium enema within 5 years, or computed tomography (CT) colonography within 10 years
2. Record of any colorectal cancer diagnosis or total colectomy

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
The proportion of individuals who complete colorectal cancer (CRC) screening within 6 months, using any of the screening modalities recommended by the United States Preventive Service Task Force (fecal immunochemical test [FIT], fecal occult blood test [FOBT], FIT-DNA, colonoscopy, flexible sigmoidoscopy, flexible sigmoidoscopy with FIT, CT colonography), assessed through electronic health record review at 6 months.

Secondary Outcome Measures

Name	Time	Method
1. Proportion of participants who return a completed mailed fecal immunochemical test (FIT) at 60 days assessed through electronic health record review at 60 days<br>2. Feasibility of a mailed FIT outreach program assessed using tracking data captured in a REDCap database to measure the proportion of bad mailing addresses, at 60 days<br>3. Acceptability of a mailed FIT outreach program assessed using semi-structured interviews with patients up to 24 months after initial FIT mailing<br>4. Cost-effectiveness of a mailed FIT outreach program assessed through comparison of the programmatic costs incurred and the number of individuals screened in the intervention arm compared to usual care (cost of intervention minus the cost of usual care, divided by the number screened in the intervention arm minus the number screened in usual care) through study completion, up to 36 months after initial FIT mailing