Neuromuscular Ultrasound Changes in Neuropathies in Correlation to Neurophysiological Findings
试验速览
- 阶段
- 不适用
- 入组人数
- 100
- 主要终点
- Nerve ultrasound
研究概览
简要总结
- Study the neuromuscular ultrasound findings in different types of neuropathies
- correlation between ultrasound and neurophysiological findings in peripheral nerve diseases
- correlation between clinical pain scale and severity of neuropathy
详细描述
Ultrasonography is a diagnostic tool that is increasingly used in the work-up of peripheral nerve disease.
As many peripheral nerves run a superficial course, especially in the arms. This is a big advantage over Magnetic Resonance Imaging that is relatively expensive, time consuming and not readily available everywhere.
Nerve cross-sectional area (CSA) can be determined at multiple sites along the nerve.
CSA can be measured at entrapment sites but also at nonentrapment sites. vascularization, echogenicity, fascicular pattern and endoneurial thickness can be investigated as well. All those modalities can give critical insight in the origin and development of various peripheral neuropathies1,2,3
Major peripheral nerves in the extremities, such as the median,ulnar thick enough to reflect the sound beam, resulting in hyperechoic on the US scan 4.
研究设计
- 研究类型
- Observational
- 观察模型
- Case Control
- 时间视角
- Cross Sectional
入排标准
- 年龄范围
- 18 Years 至 70 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •above 18 years old
- •males or females
- •diabetic complaining of neuropathy or not
- •carpal tunnel syndrome
- •Guillain-Barré syndrome
排除标准
- •Patient refuse to participate
- •The anatomy is altered due to sever trauma,tumor,or surgery
- •Severe spasticity preventing examination
结局指标
主要结局
Nerve ultrasound
时间窗: 3 years
on median and ulnar nerves
muscle Ultrasound
时间窗: 3 years
on thenar and hypothenar muscles
nerve conduction studies
时间窗: 3 years
for median and ulnar nerves (sensory and motor)
Electromyogram
时间窗: 3 years
for thenar and hypothenar
次要结局
未报告次要终点
研究者
Shahera Sayed Ahmed Abd El Maged
Resident doctor at neuropsychiatry department
Assiut University