Neuromuscular Ultrasonography Utility for Detection of Peripheral Neuropathy in Systemic Lupus Erythematosus
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 55
- 试验地点
- 1
- 主要终点
- evaluate the rule of NMUS in detection of peripheral neuropathy in SLE patient
研究概览
简要总结
This study aims to evaluate the rule of NMUS in detection of peripheral neuropathy in SLE patient and to correlate it to traditional neurophysiological studies, clinical signs and activity of SLE.
详细描述
The frequency of SLE peripheral neuropathy documented by electrophysiology has been estimated to be approximately 30%.
The term peripheral neuropathies include symmetric polyneuropathy, single and multiple mononeuropathy, and radiculopathy.
There has been increasing interest in using ultrasonography (US) to aid peripheral neuropathy diagnosis and studies have shown good correlation with other imaging modalities. US is a non-invasive and inexpensive imaging device that has become widely available as a diagnostic tool at many fields.
so systemic lupus patients were enrolled in the study , performed nerve conduction study and neuromuscular ultrasound for bil. median, ulnar, peroneal, tibial and sural nerves , on statistics the cross sections were compared in neurophusiologically affected and non affected nerves, also the sensitivity and specifity of NMUS in comparison to the traditional NCS was calculated
研究设计
- 研究类型
- Observational
- 观察模型
- Case Control
- 时间视角
- Cross Sectional
入排标准
- 年龄范围
- 17 Years 至 —(Child, Adult, Older Adult)
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •All adult SLE patients who was admitted to Rheumatology & Rehabilitation department of Assuit university hospital during time frame of study.
- •apparently healthy subjects with normal electrophysiological study
- •verbal consent, free and informed
排除标准
- •• Other causes of peripheral neuropathy:
- •Purely degenerative
- •Drug induced
结局指标
主要结局
evaluate the rule of NMUS in detection of peripheral neuropathy in SLE patient
时间窗: 6months
Measuring sensitivity and specificity of neuromuscular ultrasound in comparison to nerve conduction study
Describing the patterns of peripheral nerve affection in SLE patient
时间窗: 6months
Evaluating different studied nerves clinically, electrophyiologically and by neuromuscular ultrasonography
次要结局
未报告次要终点
研究者
Amira M elSonbaty
Principal Investigator
Assiut University
