Comparison of clonidine and magnesium sulphate in patients of ear nose and throatsurgeries.
Phase 4
Completed
- Conditions
- Health Condition 1: H679- Otitis media in diseases classified elsewhere, unspecified ear
- Registration Number
- CTRI/2019/01/017048
- Lead Sponsor
- MDM hospital
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- Not specified
- Target Recruitment
- 68
Inclusion Criteria
1)ASA group 1&2.
2)patients posted for eiective ENT surgeries who require GA and airway maintenance with ET intubation.
3)prior informed and written consent given by the patients.
4)age group between 18 to 60 years of either sex
Exclusion Criteria
1)patients not willing to be part of this study.
2)patients who are having known allergy to the study drugs.
3)SBP <100mmHg and HR <60/min.
4)pt. with history of mysthenia gravis, muscular dystrophy or any other neuromuscular disease.
5)pts. with history of epilepsy/seizure disorder.
6)pts. who are taking antihypertensive medications.
7)pregnant patients.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method to study and compare the effect of intravenous magnesium sulphate 20 mg per kg bolus followed by 10mg/kg/hr infusion and intravenous clonidine 2 microgram /kg bolus folloed by 0.5 microgram /kg/hrinfusion in attenuating the hemodynamic respnse to -1 laryngoscopy and endotracheal intubation ,extubation and recovery <br/ ><br>Timepoint: till recovery of patients
- Secondary Outcome Measures
Name Time Method anaesthetic consumption during surgeryTimepoint: till recovery of patients