A prospective comparative study of haemodynamic responses between clinical assessment guided intubation and train of four monitor guided intubation for patients undergoing elective surgery under general anaesthesia
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 发起方
- 入组人数
- 50
- 试验地点
- 1
研究概览
简要总结
Tracheal intubation triggers acute sympathetic nervous system activation manifesting as significant elevations in heart rate and blood pressure This haemodynamic surge carries clinical consequences in patients with cardiovascular compromise increasing myocardial ischemia risk and perioperative adverse events Quantitative neuromuscular monitoring using train of four TOF stimulation provides objective confirmation of complete neuromuscular blockade potentially optimizing intubating conditions and attenuating haemodynamic responses through reduced laryngeal trauma Current evidence comparing TOF guided versus clinical assessment intubation timing remains limited regarding haemodynamic outcomes and safety profiles
研究设计
- 研究类型
- Observational
入排标准
- 年龄范围
- 18.00 Year(s) 至 60.00 Year(s)（—）
- 性别
- All
入选标准
- •Patients belonging to the American Society of Anaesthesiologists physical status I and II Patients posted for elective surgery requiring general anaesthesia will be included in the study 18–60 years of age Patients of either sex.
排除标准
- •Patient refusal Patients belonging to the American Society of Anaesthesiologists physical status III and IV Anticipated difficult airway Mallampati classification III and IV Patients with hepatic renal cardiovascular neurological neuromuscular or other systemic diseases such as uncontrolled diabetes mellitus uncontrolled hypertension and patients on antipsychotic medications Pregnant females.
研究者
Ishneet Kaur Banga
Vinayaka Missions Kirupananda Variyar Medical college