PACTR202103623159030
Recruiting
Phase 1
Effect of intraoperative restrictive fluid therapy versus goal directed fluid therapy on postoperative pulmonary complications in sitting or prone neurosurgical patients
Anesthesia department faculty of medicine tanta university0 sites70 target enrollmentMarch 15, 2021
ConditionsAnaesthesia
Overview
- Phase
- Phase 1
- Intervention
- Not specified
- Conditions
- Anaesthesia
- Sponsor
- Anesthesia department faculty of medicine tanta university
- Enrollment
- 70
- Status
- Recruiting
- Last Updated
- 2 years ago
Overview
Brief Summary
No summary available.
Investigators
Eligibility Criteria
Inclusion Criteria
- •?Participants: adult patients aged 21 – 60 years.
- •?Inclusion criteria
- •Patients scheduled for neurosurgery in abnormal position (sitting or prone) with expected marked fluid shift.
- •Age from 21 to 60 years old.
- •Patients with GCS 15 (fully conscious).
- •ASA physical status II or III.
- •Competence to consent.
Exclusion Criteria
- •Patients refuse to participate in our study.
- •Patients with BMI more than 35 or less than 25\.
- •Patients with cardiac arrhythmia (limitation to use stroke volume variation as an indicator of fluid responsiveness).
- •Significant renal dysfunction (serum creatinine \> 1\.5 mg/dl).
- •Severe heart failure (New York Heart Association classification 3 or 4\).
- •Severe uncontrolled pulmonary disease.
- •Non\-extubated patients.
Outcomes
Primary Outcomes
Not specified
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