Effect of intraoperative restrictive fluid therapy versus goal directed fluid therapy on postoperative pulmonary complications in sitting or prone neurosurgical patients
Phase 1
Recruiting
- Conditions
- Anaesthesia
- Registration Number
- PACTR202103623159030
- Lead Sponsor
- Anesthesia department faculty of medicine tanta university
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- All
- Target Recruitment
- 70
Inclusion Criteria
?Participants: adult patients aged 21 – 60 years.
?Inclusion criteria
•Patients scheduled for neurosurgery in abnormal position (sitting or prone) with expected marked fluid shift.
•Age from 21 to 60 years old.
•Patients with GCS 15 (fully conscious).
•ASA physical status II or III.
•Competence to consent.
Exclusion Criteria
•Patients refuse to participate in our study.
•Patients with BMI more than 35 or less than 25.
•Patients with cardiac arrhythmia (limitation to use stroke volume variation as an indicator of fluid responsiveness).
•Significant renal dysfunction (serum creatinine > 1.5 mg/dl).
•Severe heart failure (New York Heart Association classification 3 or 4).
•Severe uncontrolled pulmonary disease.
•Non-extubated patients.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method ung ultrasound score
- Secondary Outcome Measures
Name Time Method total intraoperative fluid requirements, number of fluid boluses, number of patients requiring vasopressors, and urine output, postoperative pulmonary complications, postoperative morbidity (the proportion of patients who developed one or more complications), and ICU length of stay.