Construction and Validation of a Sepsis Prediction Model Based on Dysregulation of Host Response

Second Affiliated Hospital of Wenzhou Medical University2 sites in 1 country1,000 target enrollmentSeptember 1, 2024

ConditionsSepsis

Overview

Phase: Not Applicable
Intervention: Not specified
Conditions: Sepsis
Sponsor: Second Affiliated Hospital of Wenzhou Medical University
Enrollment: 1000
Locations: 2
Primary Endpoint: Sepsis
Status: Completed
Last Updated: last year

Overview Investigators Eligibility Criteria Outcomes Sites Similar Trials

Overview

Brief Summary

The aim of this study is to identify risk factors associated with sepsis and to construct a predictive model for sepsis. This will provide an objective theoretical and empirical foundation for the diagnosis, assessment, and management of sepsis in our country.The primary questions addressed are:

What are the risk factors for the development of sepsis? How do we improve the prognosis of sepsis?

Registry

clinicaltrials.gov

Start Date

September 1, 2024

End Date

October 17, 2024

Last Updated

last year

Study Type

Observational

Sex

All

Investigators

Sponsor

Second Affiliated Hospital of Wenzhou Medical University

Responsible Party

Sponsor

Eligibility Criteria

Inclusion Criteria

•Patients with Infection or Suspected Infection

Exclusion Criteria

•Patients with Autoimmune Diseases
•Pregnant Women
•Patients with Advanced-Stage Cancer and Systemic Metastasis

Outcomes

Primary Outcomes

Sepsis

Time Frame: 3 months

A rapid increase of 2 or more points points in the Sequential Organ Failure Assessment (SOFA) score after patient infection.SOFA score, which ranges from a minimum of 2 to a maximum of 15, indicates a worse outcome with higher scores.