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Clinical Trials/NCT02544516
NCT02544516
Completed
Not Applicable

Study on the Links Between Perception and Action in Schizophrenia, "Upside Down, Give me the Handle"

Centre Hospitalier Universitaire de Saint Etienne1 site in 1 country60 target enrollmentApril 2014

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Schizophrenic Disorders
Sponsor
Centre Hospitalier Universitaire de Saint Etienne
Enrollment
60
Locations
1
Primary Endpoint
response time
Status
Completed
Last Updated
9 years ago

Overview

Brief Summary

In schizophrenia, dislocation of psychic functions involving a loss of contact with reality is frequently found. A fragmentation of motor and sensory perceptions could be held responsible (Fuchs, 2005). However, automatic integration between perception and action is the necessary condition to be in "relationship with the world." Affordance is the experimental link between object perception and actions potentially associated (Gibson (1977, 1979) explored by Stimulus Response Compatibility (SRC) paradigm. The existence of visual motor neurons leads us to postulate that the affordance effect can be assisted by a visuomotor priming of a hand in a position to grasp. With Tucker & Ellis sensory motor compatibility task, we study the capacity of affordance in schizophrenia, as well as the impact of perceptual motor priming on these affordance effects.

Detailed Description

All participants will perform cognitive tasks: reaction time (Alert TEA, Zimmermann and Fimm, 2005), Edinburgh laterality questionnaire (Oldfield, 1971), IQ test (IQ: PM38, Raven, 1960), and the PANSS (Positive and Negative Syndrome Scale, Kay et al., 1987). Controls will only have the first three tasks (cognitive spots Alert and laterality). Then all will perform all tasks in successive order (task 1 and task 2). For both tasks, photographs of 20 objects of everyday life typical grip with one hand are presented in 4 orientations. The instruction is to say if the object is presented upright or inverted; The second task differs from the first only by the introduction of a prime: presenting a hand in position "catching" before the picture of an object

Registry
clinicaltrials.gov
Start Date
April 2014
End Date
October 2016
Last Updated
9 years ago
Study Type
Interventional
Study Design
Parallel
Sex
All

Investigators

Eligibility Criteria

Inclusion Criteria

  • For patients:
  • a DSM-IV diagnosis of schizophrenia (men or women),
  • no change in antipsychotic medication and clinical status within four weeks prior to the study

Exclusion Criteria

  • For patients and control group Inclusion criteria
  • Age ≥ 18 years et ≤ 50 years
  • Exclusion Criteria:
  • History of head trauma,
  • neurological disease with cerebral repercussion or not stabilized serious physical illness;
  • psychotropic medication,
  • disorders related to the use of a psychoactive substance (abuse, dependence or withdrawal);

Outcomes

Primary Outcomes

response time

Time Frame: day 1

The gain provided by the compatible vs incompatible conditions (ms response time)

Study Sites (1)

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