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Clinical Trials/NCT02655172
NCT02655172
Completed
Not Applicable

Study on the Links Between Action and Perception in Schizophrenia, " Have a Good Grasp of the World "

Centre Hospitalier Universitaire de Saint Etienne1 site in 1 country41 target enrollmentMay 24, 2016

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Schizophrenic Disorders
Sponsor
Centre Hospitalier Universitaire de Saint Etienne
Enrollment
41
Locations
1
Primary Endpoint
response time
Status
Completed
Last Updated
6 years ago

Overview

Brief Summary

Brief Summary: In schizophrenia, dislocation of psychic functions involving a loss of contact with reality is frequently found. A fragmentation of motor and sensory perceptions could be held responsible. However, automatic integration between perception and action is the necessary condition to be in "relationship with the world." Affordance is the experimental link between object perception and potentially associated actions (Gibson, 1977, 1979) explored by Stimulus Response Compatibility (SRC) paradigm. With Tucker & Ellis sensory motor compatibility task (1998), with a modified response device (responses given with grasp), we study the impact of motor activation on these affordance effects. In this study, a group of controls will also be included in order to understand, as precisely as possible, the mechanisms involved (i.e., interference between the perception of the object and the response gesture).

Detailed Description

Schizophrenic patients will perform: Alert TEA, (Zimmermann and Fimm, 2005), Edinburgh laterality questionnaire (Oldfield, 1971), IQ test (IQ: PM38, Raven, 1960), and the PANSS (Positive and Negative Syndrome Scale, Kay et al., 1987). Controls will only perform the laterality questionnaire. Then all will perform the affordance task, in which photographs of 20 objects of everyday life, typically graspable with one hand, are presented in 4 orientations. Participants have to respond in a graspable device, as quickly as possible, if the object is presented upright or inverted.

Registry
clinicaltrials.gov
Start Date
May 24, 2016
End Date
April 3, 2019
Last Updated
6 years ago
Study Type
Interventional
Study Design
Parallel
Sex
All

Investigators

Eligibility Criteria

Inclusion Criteria

  • For patients:
  • a DSM-IV diagnosis of schizophrenia (men or women),
  • no change in antipsychotic medication and clinical status within four weeks prior to the study
  • For patients and control group • Age ≥ 18 years et ≤ 55 years

Exclusion Criteria

  • History of head trauma,
  • neurological disease with cerebral repercussion or not stabilized serious physical illness;
  • psychotropic medication
  • disorders related to the use of a psychoactive substance (abuse, dependence or withdrawal);
  • Exclusion Criteria:
  • For patients:
  • For patients and control group
  • History of head trauma,
  • neurological disease with cerebral repercussion or not stabilized serious physical illness;
  • psychotropic medication

Outcomes

Primary Outcomes

response time

Time Frame: day 1

The gain provided by the compatible vs incompatible conditions (ms response time)

Study Sites (1)

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