JPRN-UMIN000007013已完成未知
Effect of single dose administration of trichlormethiazide on the serum level and clearance of uric acid: open-label controlled dose-escalating trial with healthy Japanese male volunteers - Effect of single dose administration of trichlormethiazide on the serum level and clearance of uric acid
Department of Clinical Pharmacology, Faculty of Medical Sciences, Kyushu University0 个研究点目标入组 8 人开始时间: 2012年1月4日最近更新:
适应症
试验速览
- 阶段
- 未知
- 状态
- 已完成
- 发起方
- 入组人数
- 8
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional
入排标准
- 年龄范围
- 20years-old 至 40years-old（—）
- 性别
- Male
入选标准
- 未提供
排除标准
- •1. Disease that should be treated 2. On medical treatment 3. History of cardiovascular disease 4. Liver disease (AST >40 or ALT >40) 5. Kidney disease (serum creatinine >1.2 mg/dL) 6. Serum uric acid level >7.0 mg/dL 7. Serum electrolyte abnormality 8. Hematocrit >50% 9. Allergic reaction to thiazide and its related diuretics 10. Systolic blood pressure <90 mmHg or >140 mmHg 11. Body weight <40 kg or >90 kg 12. Not appropriate to this study by other reasons
研究者
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