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Paravertebral Block for Postoperative Analgesia in Thoracoscopic Surgery

Not Applicable
Completed
Conditions
Pain, Postoperative
Interventions
Procedure: VATS
Procedure: PVB using PVC
Registration Number
NCT03242668
Lead Sponsor
Nguyen Trung Kien
Brief Summary

To access the analgesic efficacy of patient controlled thoracic paravertebral analgesia.

Detailed Description

The study was carried out on thirty patients who underwent video-assisted thoracic surgery.Paravertebral space was identified by loss of resistance technique under video-assisted inside thoracic space before chest close.Initiated dose of 0.3ml/kg of bupivacaine 0.125%+fentanyl 2 mcg/ml was administered then continued patient-controlled analgesia with background rate 3ml/h, bolus dose 2ml, lockout interval 10 minutes. Postoperative pain was accessed by Visual Analogue Scale at rest and on coughing; monitor the heart rate, blood pressure, respiratory rate, SpO2, arterial blood gas and spirometry in three postoperative consecutive days.

Recruitment & Eligibility

Status
COMPLETED
Sex
All
Target Recruitment
30
Inclusion Criteria
  • American Society of Anesthesiologists class I to III risk undergoing elective VATS, aged 32-72 years, scheduled for lung resection surgery.
Exclusion Criteria
  • Patients who refused to participate, less than 18 years of age, ASA physical status 3 or more,, allergy to any of the study drugs, patients having any contraindication to placement of PVB, kyphoscoliosis, presence of acute herpes zoster, chronic pain syndrome, chronic analgesic use and psychiatric disease.

Study & Design

Study Type
INTERVENTIONAL
Study Design
SINGLE_GROUP
Arm && Interventions
GroupInterventionDescription
PVB using PVC for PCA in VATSPVB using PVCThe VATS was performed.Paravertebral space was identified by loss of resistance technique combined with video-assisted inside thoracic space before chest close.PVC was inserted.Initiated dose of 0.3ml/kg of Bupivacaine Hydrochloride 1.25mg/ml and Fentanyl Citrate 2 micrograms/ml was administered then continued PCA with background rate 3ml/h, bolus dose 2ml was infused through PVC.
PVB using PVC for PCA in VATSVATSThe VATS was performed.Paravertebral space was identified by loss of resistance technique combined with video-assisted inside thoracic space before chest close.PVC was inserted.Initiated dose of 0.3ml/kg of Bupivacaine Hydrochloride 1.25mg/ml and Fentanyl Citrate 2 micrograms/ml was administered then continued PCA with background rate 3ml/h, bolus dose 2ml was infused through PVC.
PVB using PVC for PCA in VATSPCAThe VATS was performed.Paravertebral space was identified by loss of resistance technique combined with video-assisted inside thoracic space before chest close.PVC was inserted.Initiated dose of 0.3ml/kg of Bupivacaine Hydrochloride 1.25mg/ml and Fentanyl Citrate 2 micrograms/ml was administered then continued PCA with background rate 3ml/h, bolus dose 2ml was infused through PVC.
Primary Outcome Measures
NameTimeMethod
VAS score at rest and on coughing72 hours

Using VAS scale (Atrazennica)

Secondary Outcome Measures
NameTimeMethod
Arterial blood gas valuesthree postoperative consecutive days

Using Arterial blood gas analysis (STAT Model No.MCP9819-065, Martel Instruments Ltd)

The number dermatome inhibitionthree postoperative consecutive days

Using pin-prick test

Rescue analgesiathree postoperative consecutive days

When VAS score equal to or more than 4 using fentanyl to manage pain

Analgesia effects on respiratory functionthree postoperative consecutive days

Using Spirometry (Chestgraph H1 - 105,Japane) to evaluate respiratory index

Patient's satisfactionthree postoperative consecutive days

Using questionaire with 4 levels :not good,satisfied,good,very good

Trial Locations

Locations (1)

Vietnam Military Medical University

🇻🇳

Hanoi, Vietnam

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