Aggression Replacement Training (ART) for aggression-regulation disorders in adults: a randomized, controlled out-patient study

Withdrawn

Conditions: antisocial personality disorder
borderline personality disorder
Intermittent explosive disorder
10021563

Registration Number: NL-OMON35485

Lead Sponsor: niversitair Medisch Centrum Sint Radboud

Brief Summary: Not available

Detailed Description: Not available

Recruitment & Eligibility

Status: Withdrawn

Sex: Not specified

Target Recruitment: 66

Inclusion Criteria

Meeting DSM-IV criteria for antisocial personality disorder, borderline personality disorder or the integrated research criteria for Intermittent Explosive Disorder (IED-IR):

Exclusion Criteria

Lifetime history of (hypo)mania, schizophrenia, or delusional disorder

Study & Design

Study Type: Interventional

Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<p>The main outcome of aggressive behavior will be the score on the Overt<br /><br>Aggression Scale-Modified for Outpatient Use (MOAS) and Social Dysfunction and<br /><br>Aggression Scale (SDAS). The MOAS and SDAS will be completed by different<br /><br>relevant informants. A decrease of 50% on one of the questionnaires counts as a<br /><br>response to treatment, a decrease between 20-40% as a partial response and a<br /><br>decrease below 20% as a non response.</p><br>

Secondary Outcome Measures

Name	Time	Method
<p>During the pre-screening, the MOAS will be completed to examine if the<br /><br>participant meets the inclusion criteria. To examine if the participant does<br /><br>meet the inclusion and does not meet the exclusion criteria the M.I.N.I.,<br /><br>SCID-II, CIDI, PPI, EuropASI and NLV will be completed during the screening.<br /><br>For the baseline and follow-up measure of the interventions, the IOA will be<br /><br>conducted to measure social skills. The IPAS, RPQ, AQ, ZAV, SECS and PSAP will<br /><br>be used to measure the effect of the Anger Control Training. To assess the<br /><br>moral reasoning, the SRM-AV and HIT will be conducted. In addition,<br /><br>neurocognitive tasks will be conducted to include how responders and<br /><br>non-responders profiles relate to forms and correlates of aggressive behaviour. </p><br>