Effectiveness of an Adapted Physical Activity Program on Improving the Health-related Quality of Life of Women with Endometriosis in Martinique

Not Applicable

Recruiting

• Conditions: Endometriosis

• Registration Number: NCT06776627
• Lead Sponsor: University Hospital Center of Martinique

Brief Summary

There is no specific treatment for endometriosis, because the pathophysiology is poorly understood.

Adapted physical activity (APA) is recognized as a beneficial supportive care for patients suffering from chronic pathology. Adapted physical activity can play a role in managing endometriosis symptoms. Studies have shown that regular physical exercise can help reduce pain, improve quality of life and alleviate symptoms related to chronic diseases.

However, it is known that few women with endometriosis have regular physical activity because of pain, chronic fatigue that lead to activity limitation or even disability.

This study provides an opportunity to evaluate the impact of regular APA practice on improving the quality of life and symptoms of women with endometriosis in Martinique.

Based on this, APA could be included in the endometriosis care pathway in Martinique.

Detailed Description

The investigators' hypothesis is that APA improves the overall quality of life of women with endometriosis and also has a positive impact on pain, functional abilities and sleep. The effectiveness of the proposed adapted physical activity program also improves the psycho-social and professional impact of the disease in the daily lives of patients.

Study Timeline

• Study First Submitted: 2024-11-27
• Study Start: 2024-12-11
• Status Verified: 2025-01
• Study First Submitted QC: 2025-01-13
• Last Update Submitted: 2025-01-13
• Study First Posted: 2025-01-15
• Last Update Posted: 2025-01-15
• Primary Completion: 2026-03-11
• Study Completion: 2026-05-25

Recruitment & Eligibility

• Status: RECRUITING
• Sex: Female
• Target Recruitment: 51

Inclusion Criteria

• Adult woman of childbearing age,
• Clinico-radiological or clinico-histological diagnosis of endometriosis: laparoscopy with biopsy or MRI,
• History of endometriosis symptoms before diagnosis,
• Walking without technical assistance,
• Able to read and write,
• Patient wishing to improve her health by optimizing her lifestyle,
• Patient affiliated or beneficiary of a social security scheme,
• Patient having given free, informed and written consent.

Exclusion Criteria

• Acute or terminal illness,
• Recent fracture of the upper or lower limbs (< 3 months),
• Other chronic unstable or orthopedic illness that could interfere with the ability to participate in a physical activity program,
• Resting ECG at inclusion outside the normal range,
• Patients who practice moderate to intense physical activity for more than 150 minutes per week,
• Absolute contraindication to physical activity linked to severe co-morbidities,
• Patient placed under legal protection, guardianship or curatorship,
• Pregnant or breastfeeding woman.

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Primary Outcome Measures

Name	Time	Method
To evaluate the effectiveness at 12 weeks of an adapted physical activity program on the health-related quality of life of patients with endometriosis.	12 weeks	The level of health-related quality of life will be measured using the EHP-30 (Endometriosis Health Profile) questionnaire.; The minimum value is 0, and the maximum value is 100. Higher score mean a worse outcome.

Secondary Outcome Measures

Name	Time	Method
To evaluate the effectiveness at 9 weeks of an adapted physical activity program in patients with endometriosis on health-related quality of life.	12 weeks	The level of health-related quality of life will be measured using the EHP-30 (Endometriosis Health Profile) questionnaire. The minimum value is 0, and the maximum value is 100. Higher score mean a worse outcome.
To evaluate the effectiveness at 9 and 12 weeks of an adapted physical activity program in patients with endometriosis on improvement of functional capacities of physical condition, and activity level	12 weeks	Assessed by the Ricci and Gagnon questionnaire. The minimum value is 9, and the maximum value is 45. Higher score mean a better outcome.
To evaluate the effectiveness at 9 and 12 weeks of an adapted physical activity program in patients with endometriosis on improvement of grip muscle strength, flexibility, walking perimeter, and physical profile	12 weeks	Functional capacities of physical condition: measurement of walking capacity with the 6-minute walk test.
To evaluate the effectiveness at 9 and 12 weeks of an adapted physical activity program in patients with endometriosis on improvement of pain	12 weeks	Pain will be assessed by the Visual Analogue Scale. The minimum value is 0 cm, and the maximum value is 10 cm. Higher score mean a worse outcome.
To evaluate the effectiveness at 9 and 12 weeks of an adapted physical activity program in patients with endometriosis on improving sleep quality	12 weeks	Sleep quality with the questionnaire: PSQI (Pittsburgh Sleep Quality Index). The minimum value is 0, and the maximum value is 21. Higher score mean a worse outcome.
To evaluate the effectiveness at 9 and 12 weeks of an adapted physical activity program in patients with endometriosis on improving the professional, psychosocial impact of the disease in the daily lives of patients	12 weeks	The psycho-socio-family and professional impact by using the part 2 of the EHP-30 (Endometriosis Health Profile) (section A and B).

Trial Locations

Locations (1)

University Hospital Center of Martinique; 🇫🇷 Fort-de-France, France