The Influence of Neuromuscular Reversal on Neurological Physical Exam Time in Lumbar Neurosurgical Cases.

Completed

• Conditions: Neurological Complication
• Interventions: Diagnostic Test: Neurological physical exam

• Registration Number: NCT03399890
• Lead Sponsor: Ankara University

Brief Summary

Neurological physical exam is a very important outcome that should be evaluated as soon as possible after every lumbar procedures. The aim of this study was to evaluate the neurological physical examination time after lumbar procedures.

Detailed Description

Neurological physical exam is a very important outcome that should be evaluated as soon as possible after every lumbar procedures. By that early postoperative neurological complications can be revealed and early interventions planned. The aim of this study was to evaluate the neurological physical examination time after lumbar procedures. Two routinely used different reversal agents (neostigmine or sugammadex) were compared according reversal times and muscle strength on PACU admission.

Study Timeline

• Study Start: 2017-05-10
• Primary Completion: 2017-07-10
• Study Completion: 2017-10-10
• Study First Submitted: 2017-12-11
• Status Verified: 2018-01
• Study First Submitted QC: 2018-01-08
• Study First Posted: 2018-01-17
• Last Update Submitted: 2018-01-23
• Last Update Posted: 2018-01-24

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 107

Inclusion Criteria

• Lumber surgery
• ASA I-II
• Elective surgery

Exclusion Criteria

• Emergency cases
• Age lower than 18
• Age higher than 65
• Patient with existing neurological deficit
• Patient with existing renal insufficiency

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Arm && Interventions

Group	Intervention	Description
Group S	Neurological physical exam	Group S: Group sugammadex Patients in this group received sugammadex at the end of the surgery, as neuromuscular reversal agent. Neurological physical exam time was recorded.
Group N	Neurological physical exam	Group N: Group Neostigmine Patients in this group received neostigmine at the end of the surgeryas neuromuscular reversal agent. Neurological physical exam time was recorded.

Primary Outcome Measures

Name	Time	Method
Neurological physical examination time	postoperative first 30 minutes	Neurological physical examination time

Secondary Outcome Measures

Name	Time	Method
Muscle strength at PACU transfer	postoperative first 60 minutes	Muscle strength at PACU transfer (evaluated with a 5 point scale) 0/5: no contraction in muscles 1/5: muscle flicker but no movement 2/5: movement possible bıt not against gravity (test the joint in its horizontal plane) 3/5: moment possible against gravity but not against resistance by the examiner 4/5: movement possible against resistance by the examiner 5/5: normal strength

Trial Locations

Locations (1)

Ankara University Faculty of Medicine; 🇹🇷 Ankara, Turkey