Continous Assessment of Cerebral Autoregulation With Near-infrared Spectroscopy

• Conditions: Cerebral Blood Flow; Cerebral Perfusion Pressure
• Interventions: Device: measure TOI and BP

• Registration Number: NCT02959008
• Lead Sponsor: Yu Liyun

Brief Summary

Cerebral autoregulation can be explained by a tight coupling between oxygen supply and demand of the brain, and is essential to maintain a constant cerebral blood flow (CBF) in the context of changes in cerebral perfusion pressure. In this study, investigators use Near-infrared spectroscopy (NIRS) to monitor cerebral autoregulation.

Detailed Description

Near-infrared spectroscopy (NIRS) is a noninvasive technology that real-time monitors cerebral tissue oxygenation index (TOI). Investigators use Near-infrared spectroscopy (NIRS) to monitor cerebral autoregulation of hypertensive participants and non-hypertensive participants.

Study Timeline

• Status Verified: 2016-11
• Study First Submitted: 2016-11-05
• Study First Submitted QC: 2016-11-05
• Study First Posted: 2016-11-08
• Last Update Submitted: 2016-11-15
• Last Update Posted: 2016-11-16
• Study Start: 2016-12
• Primary Completion: 2018-12
• Study Completion: 2019-12

Recruitment & Eligibility

• Status: UNKNOWN
• Sex: All
• Target Recruitment: 40

Inclusion Criteria

• health people, or people with hypertension

Exclusion Criteria

• diabetes, anemia, liver disease, kidney disease.

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Arm && Interventions

Group	Intervention	Description
normal	measure TOI and BP	Human without hypertension, diabetes, anemia, liver disease and kidney disease. The group will measure TOI and BP.
hypertension	measure TOI and BP	Human only have hypertension, without diabetes, anemia, liver disease and kidney disease. Hypertension group will measure TOI and BP.

Primary Outcome Measures

Name	Time	Method
range of cerebral autoregulation	30min