Prevention of Dementia in Older Adults- Tiruvalla Interventional Study in Ageing
- Conditions
- Health Condition 1: F028- Dementia in other diseases classified elsewhere
- Registration Number
- CTRI/2023/11/060181
- Lead Sponsor
- IH
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
Individuals between 60-75 years old, willing to participate and comply with all the study evaluation and intervention procedures
CAIDE (Cardiovascular Risk Factors, Aging and Dementia) Dementia Risk Score of 6 points or higher
Mini Mental State Examination, MMSE <26 and >20
Barthel index < 90.
Geriatric Depression Scale = 9
Dementia or Moderate Cognitive impairment (MMSE < 20).
Disorders that may affect safe involvement in the intervention (eg, malignancy, symptomatic cardiovascular disease, Large vessel stroke in the past two years, History of transient ischemia attack (TIA) or small vessel stroke in the last 6 months, revascularisation within 1 year previously, severe loss of vision, hearing, or communicative ability)
Coincident participation in another intervention trial.
Recent ( < 3 months) bone fracture.
History of hip fracture, joint replacement, or spinal surgery in the last 6 months
Clinically significant abnormalities in laboratory blood tests as per the judgment of the site study clinician.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Cognitive ability will be assessed using Addenbrookes cognitive examinationTimepoint: Cognitive ability will be assessed at baseline, 6 months, 12 months and 24 months.
- Secondary Outcome Measures
Name Time Method Depresiion, quality of life , ADLTimepoint: <br/ ><br>measurements will be made at baseline, 12 months & 24 months