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临床试验/ACTRN12609000943246
ACTRN12609000943246招募中不适用

Effects of acute and longer-term energy restriction in lean and obese subjects on antropyloroduodenal motility, gut hormones, appetite and energy intake in response to duodenal nutrients and on oral fat perception

A/Prof Christine Feinle-Bisset0 个研究点目标入组 30 人开始时间: 2009年11月3日最近更新:
适应症

试验速览

阶段
不适用
状态
招募中
发起方
入组人数
30

研究概览

简要总结

暂无简介。

研究设计

研究类型
Interventional
分配方式
Non-randomised trial
主要目的
Prevention
盲法
Open (masking not used)

入排标准

年龄范围
18 Years 至 55 Years(—)
性别
Male

入选标准

  • Subjects will all be males between age 18 -55 years, with a body mass index (BMI) of 18 - 25 kg/m2 for lean and between 30 -35 kg/m2 for obese. Lean subjects will be required to be unrestrained eaters, consume less than 20g of alcohol per week, be non-smokers, free of gastrointestinal or chronic disease and not currently taking medication.

排除标准

  • Each subject will be questioned prior to the study to exclude:
  • (1)significant gastrointestinal symptoms; disease or surgery
  • (2)current use of medications which may alter gastrointestinal motor function or appetite
  • (3)diabetes mellitus (fasting glucose >6.9 mmol/l and/or glycated haemoglobin =6.2 %)
  • (4)epilepsy
  • (5)cardiovascular or respiratory disease
  • (6)any other significant illness as assessed by the investigator
  • (7)allergy to local anaesthetic
  • (8)intake of > 20 g alcohol on a daily basis
  • (9)smokers
  • (10)individuals with food intolerances, allergies or vegetarians

研究者

发起方
A/Prof Christine Feinle-Bisset

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