A human study for investigating effects of Lycium barbarum extract consumption on antioxidative capacity in hypercholesterolemic adults
- Conditions
- Not Applicable
- Registration Number
- KCT0000729
- Lead Sponsor
- Ewha Womans University
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- All
- Target Recruitment
- 54
1) Subject who voluntarily agrees to participate and signs in informed consent form
2) Age: = 30 years
3) BMI: = 23kg/m2 and < 30kg/m2
4) Plasma LDL cholesterol levels = 130mg/dl
1) Continuous consumption of dietary supplements or medicine which can affect antioxidative capacity within 4 weeks before the first visit
2) Continuous consumption of Lycium barbarum within 4 weeks before the first visit
3) Continuous administration of drugs which can affect antioxidative capacity within 4 weeks before the first visit (hypolipidemic, antiinflammatory drug, hypotensive, antibiotics, aspirin, hypoglycemic, anticoagulant)
4) Subject with following diseases and past medical history within 2 years before the first visit (Hypertension, diabetes, atherosclerosis, chronic inflammatory disease, CVD, renal disease, liver disease, thyroid disease, malignant tumor, mental illness)
5) Subject who loses weight over 4kg within 30 day before the first visit
6) Consumption of alcohol (= 140g/week)
7) Smoker (= 10 cigarettes/day)
8) Excessive exercise (= 7 hours/week)
9) Pregnant women, lactating women, or menopausal women with hormone therapy
10) Participation in other human study within 4 weeks before the first visit
11) Subjects with hypersensitivity to test materials
12) Any condition that the principal investigator believes may put the subjects at undue risk
Study & Design
- Study Type
- Interventional Study
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Antioxidative markers
- Secondary Outcome Measures
Name Time Method ipid profiles, etc.