EUCTR2009-013481-10-NL进行中（未招募）不适用
Pharmacokinetics of high dose Ropivacaine with and without epinephrine for combined femoral and sciatic nerve block in lower extremity surgery. A pilot study. - RopiPilot
适应症
相关药物
试验速览
- 阶段
- 不适用
- 状态
- 进行中（未招募）
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional clinical trial of medicinal product
入排标准
- 性别
- All
入选标准
- •- Patients = 18 years, = 60 years
- •- Body Weight = 70 kg
- •- ASA classification I – III
- •- Patients undergoing combined femoral and sciatic nerve block for lower extremity orthopaedic surgery
- •- Who will be admitted for at least 48 hours
- •- Written informed consent
- •Are the trial subjects under 18? no
- •Number of subjects for this age range:
- •F.1.2 Adults (18-64 years) yes
- •F.1.2.1 Number of subjects for this age range
- •F.1.3 Elderly (>=65 years) no
- •F.1.3.1 Number of subjects for this age range
排除标准
- •- Contra-indications for regional anesthesia (infection at the injection site, coagulopathy)
- •- Known hypersensitivity to amide-type local anesthetics
- •- Known history of peripheral neuropathy
- •- Hepatic or renal insufficiency
- •- Use of fluvoxamine, ciprofloxacin, ketoconazole, erythromycin, clarithromycin, itraconazole, or rifampicin because of their effect on ropivacaine clearance.
研究者
相似试验
尚未招募
4 期
Pharmacokinetics of high dose Ropivacaine with and without epinephrine for combined femoral and sciatic nerve block in lower extremity surgery. A pilot study.orthopaedic surgery of the lower extremity10005944NL-OMON33042Sint Maartenskliniek12
已完成
不适用
Farmacokinetiek van ropivacaïne met en zonder adrenaline bij hoge doseringen voor n. femoralis en ischiadicus blok bij orthopedische chirurgie van de onderste extremiteit.combined femoral and sciatic nerve block for lower extremity orthopedic surgeryNL-OMON21564Sint Maartenskliniek Nijmegen, The Netherlands12
进行中（未招募）
1 期
High dose local anesthetic compared to moderate dose for pain relief after surgeryPostoperative painMedDRA version: 20.0Level: PTClassification code 10000081Term: Abdominal painSystem Organ Class: 10017947 - Gastrointestinal disordersEUCTR2020-002699-10-DK28
进行中（未招募）
1 期
Study to describe the processing of ropivacaine in the body when injected in the knee for pain treatment in total knee arthroplastypatients receiving primary total knee replacementEUCTR2017-000180-32-NLSint Maartenskliniek Nijmegen20
已完成
不适用
CLINICAL PHARMACOKINETICS OF ROPIVACAINE USING LOCAL INFILTRATION ANESTHESIA (LIA) TECHNIQUE IN THE TOTAL KNEE ARTHROPLASTY: A PILOT STUDYTotal knee arthroplasty (total knee replacement)10005944NL-OMON37901Reinier de Graaf Groep10