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临床试验/NCT06589583
NCT06589583已完成不适用

Rrol of Deep Learning Algorithm in Assessment and Management of Scoliosis

Delta University for Science and Technology1 个研究点 分布在 1 个国家目标入组 5,000 人开始时间: 2024年7月1日最近更新:
适应症

试验速览

阶段
不适用
状态
已完成
入组人数
5,000
试验地点
1
主要终点
test the validity and reliability of software

研究概览

简要总结

The aim of the study to use artificial intelligence technology in assessment of scoliosis degree of severity and to personalize for treatment plan for each pa tient .

详细描述

Although attention in AI related to healthcare is expanding, there hast been much progress in translating or implementing these technologies for clinical usage. Therefore, as we conduct our research, we will open a new field of study for the integration of artificial intelligence (AI) in medical assessment tools and physical therapy field. This will save physiotherapists time and effort for developing Proper evaluations and conduction of treatment plans, benefit patients and the country overall by lowering the financial burden associated with making accurate evaluations and management for these cases, and provide clear, objective evaluations for the majority of spinal scoliosis deformities as well as appropriate personalization for treatment plans.

Martial and Methods

  1. Experiment martials This section presents the findings of the research, detailing the methodologies employed and the outcomes obtained. The analysis begins with an overview of the dataset used, followed by the preprocessing steps undertaken to ensure data quality and suitability for model training. then delve into the various approaches and models selected for this study, including both custom Convolutional Neural Networks (CNNs) and pre-trained models utilized through transfer learning. Each model is assessed based on its performance, and discuss the experimental setup and evaluation metrics used to measure effectiveness. Finally, presenting the experimental results, providing a comprehensive analysis of model accuracy, precision, recall, and other relevant metrics.

2.1 Dataset collection The data of the subjects were divided for 2 groups. Group (A) normal spine total X-ray consisted of 664 image and group (B) scoliotic patients x-ray consisted of 4307 images. All spinal X-ray involved in this study were retrospectively compiled from manifold sources, including BUU Datasets , Kaggle, Mendeley Data, Huggingface, Dropbox , and Roboflow, ensuring a diverse and comprehensive collection of scoliosis-related images. Patient with scoliosis were (1) diagnosed with scoliosis for different etiology, (2) Clear X- Ray for spine for all spinal curvatures including; cervical, thoracic and lumber. (3) C shaped and double C shape scoliosis. (4) mild, moderate and sever scoliotic degrees. (5) Adolescents with mean age 17(6) Both gender(male and female). 2. Purposed methodology 2.1 Data Augmentation To address the issue of limited data, we employed data augmentation to artificially expand our dataset. This technique involves generating new training samples by applying various transformations to the existing images, such as flipping, scaling, and rotating. These augmentations not only increase the dataset size but also play a crucial role in enhancing the model ability to generalize by exposing it to a wider variety of image variations. By simulating different viewing conditions and distortions, data augmentation helps the model become more robust to changes in image orientation, scale, and other variations that it may encounter in real-world scenarios. This process is particularly important in medical image analysis, where acquiring large, diverse datasets can be challenging. Data augmentation ensures that the model does not overfit to the limited original dataset and instead learns to recognize the underlying patterns that are indicative of scoliosis, ultimately improving its performance and reliability.

Original images Flipped image Rotated image Scaled image

研究设计

研究类型
Observational
观察模型
Other
时间视角
Retrospective

入排标准

年龄范围
15 Years 至 37 Years(Child, Adult)
性别
All
接受健康志愿者

入选标准

  • ). Patient with scoliosis were
  • diagnosed with scoliosis for different etiology.
  • Clear X- Ray for spine for all spinal curvatures including; cervical, thoracic and lumber(PA)view.
  • C shaped and double C shape scoliosis such as (Thoracolumbar-cervicothoracic scoliosis).
  • Mild, moderate and severe scoliotic degrees.
  • Adolescents with mean age 17 years old
  • Male and female gender

排除标准

  • children with scoliosis
  • age less than 12 years old .
  • lateral view spine x- ray.

结局指标

主要结局

test the validity and reliability of software

时间窗: 2 months

ability of the models to differentiate normal from scoliotic x-ray (automatic classification) which helps in diagnosis of scoliosis by identifying the curve .

determine degree of curve severity via measurement cobb's angle by degree

时间窗: 2 months

for grading of scoliosis severity (mild or moderate or sever )

suggested treatment program according to each patient need .in form points

时间窗: 2 moths

in case of mild scoliosis the intervention will be conservative on other hand in moderate curve intervention will be conservatives and orthotic management while in sever suggested surgical interface.

次要结局

未报告次要终点

研究者

申办方类型
Other
责任方
Principal Investigator
主要研究者

Dina S. Noaman

Demonstrator of pediatrics and its surgery

Delta University for Science and Technology

研究点 (1)

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