Preventive Effects of Different Volumes of High-Intensity Interval Training on Risk Factors for MS in Overweight Young Women

Not Applicable

Completed

• Conditions: Metabolic Syndrome

• Registration Number: NCT06664398
• Lead Sponsor: Beijing Sport University

Brief Summary

This study investigates the effects of different volumes of high-intensity interval training on risk factors for metabolic syndrome in overweight young women.

Detailed Description

The sedentary and inactive female overweight subjects, aged 18 to 30 years, were randomly divided into three groups: high volume high-intensity interval training group (4HIIT group), low volume high-intensity interval training group (1HIIT group) and control group (CON group). Human morphological measures, blood pressure, insulin resistance, blood analysis, and cardiorespiratory fitness were measured at baseline and after exercise intervention.

Study Timeline

• Study Start: 2021-04-14
• Primary Completion: 2021-07-30
• Study Completion: 2021-11-30
• Status Verified: 2024-10
• Study First Submitted: 2024-10-28
• Study First Submitted QC: 2024-10-28
• Last Update Submitted: 2024-10-28
• Study First Posted: 2024-10-29
• Last Update Posted: 2024-10-29

Recruitment & Eligibility

• Status: COMPLETED
• Sex: Female
• Target Recruitment: 30

Inclusion Criteria

• Women aged 18-30 years;
• BMI≥24kg/m2, indicating overweight and high risk of metabolic syndrome;
• Maintaining a stable body weight for the three months prior to the study.

Exclusion Criteria

• Regular participation in physical exercise (≥3 times/week, exercise time≥30min/time);
• Any respiratory, musculoskeletal, or cardiovascular diseases;
• Medical or other contraindications for exercise;
• Taking medications that affect metabolism;
• Smoking and/or drinking habits.

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Primary Outcome Measures

Name	Time	Method
Weight	8 weeks	Changes in Weight before and after intervention.
Body Mass Index (BMI)	8 weeks	Changes in BMI before and after intervention.
body fat percentage	8 weeks	Changes in body fat percentage before and after intervention.
waist circumference (WC)	8 weeks	Changes in WC before and after intervention.
Systolic blood pressure (SBP)	8 weeks	Changes in SBP before and after intervention.
Diastolic blood pressure (DBP)	8 weeks	Changes in DBP before and after intervention.
Fasting plasma glucose (FPG)	8 weeks	Changes in FPG before and after intervention.
Triglyceride (TG)	8 weeks	Changes in TG before and after intervention.
High-density lipoprotein cholesterol (HDL-C)	8 weeks	Changes in HDL-C before and after intervention.

Secondary Outcome Measures

Name	Time	Method
Non high-density lipoprotein cholesterol (Non HDL-C)	8 weeks	Changes in HDL-C before and after intervention.
Insulin	8 weeks	Changes in insulin before and after intervention.
Homeostatic model assessment for insulin resistance (HOMA-IR)	8 weeks	12、Homeostatic model assessment for insulin resistance (HOMA-IR) Changes in HOMA-IR before and after intervention.
Triglyceride-glucose (TyG) index	8 weeks	Changes in TyG index before and after intervention.
Triglyceride-to-high density lipoprotein cholesterol ratio (TG/HDL-C ratio)	8 weeks	Changes in TG/HDL-C ratio before and after intervention.
Visceral fat area (VFA)	8 weeks	Changes in VFA before and after intervention.

Trial Locations

Locations (1)

School of Sports Medicine and Rehabilitation, Beijing Sport University; 🇨🇳 Beijing, China