Vascular Phenotypes in a Geriatric Populatio

• Conditions: <p>Memory complaints, microvascular damage, macrovascular damage</p>

• Registration Number: NL-OMON29291
• Lead Sponsor: Amsterdam University Medical Center

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Last Update Posted: 8 July 2024

Recruitment & Eligibility

• Status: Pending
• Sex: Not specified
• Target Recruitment: 150

Inclusion Criteria

Age of 65 years or older
-Signed informed consent for the general protocol (METc 2017.148)

Exclusion Criteria

-Insufficient proficiency of the Dutch language.
- Severe cognitive impairment: MMSE score < 16.

Study & Design

• Study Type: Observational non invasive
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<p>The main study parameters are different vascular phenotypes, based on measurements of macro- and microvascular function.</p>

Secondary Outcome Measures

Name	Time	Method
<p>Secondary study parameters are cognitive functioning, as assessed by neuropsychological assessment, physical performance (handgrip strength, gait speed and Short Physical Performance Battery) and functional outcomes: activities of daily living (ADL) and instrumental ADL (iADL) dependence levels, quality of life, (serious) adverse events and mortality.</p>