A randomized control trial to evaluate the effect of addition of intrathecal clonidine to hyperbaric bupivacaine on postoperative pain after lower segment caesarean sectio
Not Applicable
Completed
- Conditions
- Health Condition 1: null- healthy parturients
- Registration Number
- CTRI/2012/09/002946
- Lead Sponsor
- ady Hardinge Medical College Associated Shrimati Sucheta Kriplani Hospital
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- Not specified
- Target Recruitment
- 105
Inclusion Criteria
105 healthy parturients (ASA physical status I and II) carrying a singleton fetus at term, scheduled to undergo elective lower segment caesarean section under spinal anaesthesia
Exclusion Criteria
who refused spinal anaesthesia, had any contraindication to regional anaesthesia, had fetal distress, preterm gestation, hypertensive disorders of pregnancy, multiple pregnancy, weighed more than 90 kg, were less than 140 cm or more than 170 cm in height, had any major co-morbidity or if they were unable to communicate in either english or hindi language
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Duration of postoperative analgesiaTimepoint: the time from intrathecal injection of the drug to the time when patient first requests analgesia in the postoperative period
- Secondary Outcome Measures
Name Time Method Heart rate, Systolic Blood Pressure, Diastolic Blood Pressure, Mean Arterial Blood Pressure,Onset and duration of sensory block and motor blockade, Level of sedation, Quality of surgical anaesthesia, Supplemental drug and vasopressor requirement, Side effects, Umbilical artery blood gas analysis and neonatal Apgar scoreTimepoint: Time from giving spinal to time when Hollmen scale 3 was achieved at T6 level as onset of sensory block <br/ ><br>Time from giving spinal to time Bromage scale 4 was achieved as onset of motor block <br/ ><br>Apgar at 1 min and at 5 min <br/ ><br>Maternal sedation every 15 min <br/ ><br>Duration of sensory block as time from IT injection to time till regression below T12 Duration of motor blockade as time from IT injection to time till Bromage scale reaches 1